Recombinant Treponema pallidum protein Tp47 increases permeability of vascular endothelial cells through inducing uPA

Recombinant Treponema pallidum protein Tp47 increases permeability of vascular endothelial cells through inducing uPA

Objective To investigate the effect of recombinant Treponema pallidum protein Tp47 (rTpp47) on the expression of uPA by THP-1 macrophages and on the permeability of human umbilical vein/vascular endothelial cells(HUVECs). Methods THP-1 cells were stimulated with rTpp47 for 24 hours and then the cult...

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Bibliographic Details
Main Author: YU Bao-dan, CHEN Cong, KE Wu-jian, LYU Ping
Format: Article
Language:zho
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2022-01-01
Series:Jichu yixue yu linchuang
Subjects:
treponema pallidum|recombinant tp protein tp47(rtpp47)|urokinase-type plasminogen activator(upa)|macrophages|human umbilical vein/vascular endothelial cells(huvecs)
Online Access:http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-1-120.pdf

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