Granulosa cell tumor of the testis in a newborn
Testicular neoplasms are uncommon tumors of childhood. These tumors comprise the germ cell tumors, and other tumors that may originate from histological testicular components, which are unrelated to the germinal lineage. Among the latter are the sex cord-stromal tumors (SCST), an important entity in...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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University of São Paulo
2014-03-01
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| Series: | Autopsy and Case Reports |
| Subjects: | |
| Online Access: | http://www.revistas.usp.br/autopsy/article/view/81209 |
| _version_ | 1818280658461523968 |
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| author | Oliver Rojas Claros Américo Toshiaki Sakai Horácio Consolmagno Marcos de Paula Nogueira Leonardo Abreu Testagrossa Oscar Eduardo Hidetoshi Fugita |
| author_facet | Oliver Rojas Claros Américo Toshiaki Sakai Horácio Consolmagno Marcos de Paula Nogueira Leonardo Abreu Testagrossa Oscar Eduardo Hidetoshi Fugita |
| author_sort | Oliver Rojas Claros |
| collection | DOAJ |
| description | Testicular neoplasms are uncommon tumors of childhood. These tumors comprise the germ cell tumors, and other tumors that may originate from histological testicular components, which are unrelated to the germinal lineage. Among the latter are the sex cord-stromal tumors (SCST), an important entity in newborns. SCSTs comprise, among others, granulosa cell tumors, which are more common in the ovary, but in rare cases may develop in the testis. The prognosis is excellent since it is universally benign. Diagnosis, which is sometimes challenging, is usually made after orchiectomy and pathological examination, which is characterized by morphological features and positive expression of inhibin, calretinin, and vimentin, and negative for alpha-fetoprotein. The authors present the case of a newborn with a right enlarged testis detected during the first examination after birth. Ultrasonography showed a heterogeneous solid/cystic mass in the right testis, without retroperitoneal lymphadenopathy. A right inguinal orchiectomy was performed 21 hours after birth. Pathologic examination revealed a juvenile granulosa cell tumor of the right testicle. After 4 years of follow-up, as expected, the child presented an uneventful outcome. |
| first_indexed | 2024-12-12T23:52:43Z |
| format | Article |
| id | doaj.art-b334139452b04d71a045930e63083d05 |
| institution | Directory Open Access Journal |
| issn | 2236-1960 |
| language | English |
| last_indexed | 2024-12-12T23:52:43Z |
| publishDate | 2014-03-01 |
| publisher | University of São Paulo |
| record_format | Article |
| series | Autopsy and Case Reports |
| spelling | doaj.art-b334139452b04d71a045930e63083d052022-12-22T00:06:38ZengUniversity of São PauloAutopsy and Case Reports2236-19602014-03-014110.4322/acr.%y.8120977832Granulosa cell tumor of the testis in a newbornOliver Rojas Claros0Américo Toshiaki Sakai1Horácio Consolmagno2Marcos de Paula Nogueira3Leonardo Abreu Testagrossa4Oscar Eduardo Hidetoshi Fugita5Divisão de Clínica Cirúrgica do Hospital Universitário da USPDivisão de Clínica Cirúrgica do Hospital Universitário da USPDivisão de Clínica Cirúrgica do Hospital Universitário da USPDivisão de Clínica Cirúrgica do Hospital Universitário da USPDepartamento de Patologia do Hospital das Clínicas da Fac. de Medicina da USPDivisão de Clínica Cirúrgica do Hospital Universitário da USPTesticular neoplasms are uncommon tumors of childhood. These tumors comprise the germ cell tumors, and other tumors that may originate from histological testicular components, which are unrelated to the germinal lineage. Among the latter are the sex cord-stromal tumors (SCST), an important entity in newborns. SCSTs comprise, among others, granulosa cell tumors, which are more common in the ovary, but in rare cases may develop in the testis. The prognosis is excellent since it is universally benign. Diagnosis, which is sometimes challenging, is usually made after orchiectomy and pathological examination, which is characterized by morphological features and positive expression of inhibin, calretinin, and vimentin, and negative for alpha-fetoprotein. The authors present the case of a newborn with a right enlarged testis detected during the first examination after birth. Ultrasonography showed a heterogeneous solid/cystic mass in the right testis, without retroperitoneal lymphadenopathy. A right inguinal orchiectomy was performed 21 hours after birth. Pathologic examination revealed a juvenile granulosa cell tumor of the right testicle. After 4 years of follow-up, as expected, the child presented an uneventful outcome.http://www.revistas.usp.br/autopsy/article/view/81209Sex Cord-Gonadal Stromal TumorsGranulosa Cell TumorTesticular NeoplasmsInfantNewbornTestis. |
| spellingShingle | Oliver Rojas Claros Américo Toshiaki Sakai Horácio Consolmagno Marcos de Paula Nogueira Leonardo Abreu Testagrossa Oscar Eduardo Hidetoshi Fugita Granulosa cell tumor of the testis in a newborn Autopsy and Case Reports Sex Cord-Gonadal Stromal Tumors Granulosa Cell Tumor Testicular Neoplasms Infant Newborn Testis. |
| title | Granulosa cell tumor of the testis in a newborn |
| title_full | Granulosa cell tumor of the testis in a newborn |
| title_fullStr | Granulosa cell tumor of the testis in a newborn |
| title_full_unstemmed | Granulosa cell tumor of the testis in a newborn |
| title_short | Granulosa cell tumor of the testis in a newborn |
| title_sort | granulosa cell tumor of the testis in a newborn |
| topic | Sex Cord-Gonadal Stromal Tumors Granulosa Cell Tumor Testicular Neoplasms Infant Newborn Testis. |
| url | http://www.revistas.usp.br/autopsy/article/view/81209 |
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