HIV-associated lymphomas
A steady worldwide increase in the number of people living with HIV (PLHIV) and diagnostic methods requires a separate review of patient-specific nosologies, including lymphoproliferative diseases, some of which are directly associated with the virus due to its oncogenic effect and those that do not...
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Format: | Article |
Language: | English |
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Bashkir State Medical University
2023-01-01
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Series: | Креативная хирургия и онкология |
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Online Access: | https://www.surgonco.ru/jour/article/view/739 |
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author | G. A. Dudina Ch. K. Mabudzada A. A. Ogannisyan V. N. Nemikin |
author_facet | G. A. Dudina Ch. K. Mabudzada A. A. Ogannisyan V. N. Nemikin |
author_sort | G. A. Dudina |
collection | DOAJ |
description | A steady worldwide increase in the number of people living with HIV (PLHIV) and diagnostic methods requires a separate review of patient-specific nosologies, including lymphoproliferative diseases, some of which are directly associated with the virus due to its oncogenic effect and those that do not relate directly to HIV but introduce nuances to diagnostic and therapeutic approaches when a patient is HIV-positive. Towards this, the paper generally reviews lymphomas in PLHIV, presents the WHO classification of HIV-associated lymphomas, describes a contemporary view of the known mechanisms of pathogenesis, including the role of opportunistic infections, and general principles of diagnostic and therapeutic tactics, provides recommendations on modifying the doses of chemotherapy correlated with the immune status and on preventing CNS involvement. Specific types of lymphoma (Burkitt’s lymphoma, diff use large B-cell lymphoma) are considered separately, including those most frequently associated with patients living with HIV (primary effusion lymphoma, plasmablastic lymphoma, primary central nervous system lymphoma), but rare in the uninfected population. |
first_indexed | 2024-04-10T00:58:50Z |
format | Article |
id | doaj.art-b335dacf6edd416db0eb98af47cfe803 |
institution | Directory Open Access Journal |
issn | 2307-0501 2076-3093 |
language | English |
last_indexed | 2024-04-10T00:58:50Z |
publishDate | 2023-01-01 |
publisher | Bashkir State Medical University |
record_format | Article |
series | Креативная хирургия и онкология |
spelling | doaj.art-b335dacf6edd416db0eb98af47cfe8032023-03-13T10:01:10ZengBashkir State Medical UniversityКреативная хирургия и онкология2307-05012076-30932023-01-0112432032710.24060/2076-3093-2022-12-4-320-327504HIV-associated lymphomasG. A. Dudina0Ch. K. Mabudzada1A. A. Ogannisyan2V. N. Nemikin3Московский клинический научный центр им. А.С. Логинова; Российский национальный исследовательский медицинский университет имени Н.И. ПироговаМосковский клинический научный центр им. А.С. ЛогиноваМосковский клинический научный центр им. А.С. ЛогиноваМосковский клинический научный центр им. А.С. ЛогиноваA steady worldwide increase in the number of people living with HIV (PLHIV) and diagnostic methods requires a separate review of patient-specific nosologies, including lymphoproliferative diseases, some of which are directly associated with the virus due to its oncogenic effect and those that do not relate directly to HIV but introduce nuances to diagnostic and therapeutic approaches when a patient is HIV-positive. Towards this, the paper generally reviews lymphomas in PLHIV, presents the WHO classification of HIV-associated lymphomas, describes a contemporary view of the known mechanisms of pathogenesis, including the role of opportunistic infections, and general principles of diagnostic and therapeutic tactics, provides recommendations on modifying the doses of chemotherapy correlated with the immune status and on preventing CNS involvement. Specific types of lymphoma (Burkitt’s lymphoma, diff use large B-cell lymphoma) are considered separately, including those most frequently associated with patients living with HIV (primary effusion lymphoma, plasmablastic lymphoma, primary central nervous system lymphoma), but rare in the uninfected population.https://www.surgonco.ru/jour/article/view/739вичлимфомавич-ассоциированная лимфомаантиретровирусная терапиявирус эпштей на — баррсd4+ лимфоцитылимфопролиферативные болезнилимфома беркиттадиффузная b-крупноклеточная лимфома |
spellingShingle | G. A. Dudina Ch. K. Mabudzada A. A. Ogannisyan V. N. Nemikin HIV-associated lymphomas Креативная хирургия и онкология вич лимфома вич-ассоциированная лимфома антиретровирусная терапия вирус эпштей на — барр сd4+ лимфоциты лимфопролиферативные болезни лимфома беркитта диффузная b-крупноклеточная лимфома |
title | HIV-associated lymphomas |
title_full | HIV-associated lymphomas |
title_fullStr | HIV-associated lymphomas |
title_full_unstemmed | HIV-associated lymphomas |
title_short | HIV-associated lymphomas |
title_sort | hiv associated lymphomas |
topic | вич лимфома вич-ассоциированная лимфома антиретровирусная терапия вирус эпштей на — барр сd4+ лимфоциты лимфопролиферативные болезни лимфома беркитта диффузная b-крупноклеточная лимфома |
url | https://www.surgonco.ru/jour/article/view/739 |
work_keys_str_mv | AT gadudina hivassociatedlymphomas AT chkmabudzada hivassociatedlymphomas AT aaogannisyan hivassociatedlymphomas AT vnnemikin hivassociatedlymphomas |