Multirate Spectral Domain Optical Coherence Tomography

Optical coherence tomography is state-of-the-art in non-invasive imaging of biological structures. Spectral Domain Optical Coherence Tomography is the popularly used variation of this technique, but its performance is limited by the bandwidth and resolution of the system. In this work, we theoretica...

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Main Authors: Prabhav Gaur, Andrew Grieco, Yeshaiahu Fainman
Format: Article
Language:English
Published: IEEE 2023-01-01
Series:IEEE Photonics Journal
Subjects:
Online Access:https://ieeexplore.ieee.org/document/10246288/
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author Prabhav Gaur
Andrew Grieco
Yeshaiahu Fainman
author_facet Prabhav Gaur
Andrew Grieco
Yeshaiahu Fainman
author_sort Prabhav Gaur
collection DOAJ
description Optical coherence tomography is state-of-the-art in non-invasive imaging of biological structures. Spectral Domain Optical Coherence Tomography is the popularly used variation of this technique, but its performance is limited by the bandwidth and resolution of the system. In this work, we theoretically formulate the use of phase modulators and delay lines to act as filters on the tomography system and scan multiple channels. Various channels are then combined in a digital computer using filter bank theory to improve the sampling rate. The combination of multiple channels allows for increasing the axial resolution and maximum unambiguous range beyond the Nyquist limit. We then simulate the multirate spectral domain optical coherence tomography with 2 channels. We show that a single delay line can improve the axial resolution while a pair of phase modulators can improve the maximum unambiguous range of the system. We also show the use of multirate filter banks to carry out this process. Thus, by using a few extra components in the spectral domain optical coherence tomography, its performance can be increased manifold depending on the number of channels used. The extra cost is the time taken to perform the extra scans that is trivial for stationary objects like biological tissues.
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spelling doaj.art-b337941e4e7d4be5a51df086a7b063972023-09-20T23:00:08ZengIEEEIEEE Photonics Journal1943-06552023-01-0115511010.1109/JPHOT.2023.331352110246288Multirate Spectral Domain Optical Coherence TomographyPrabhav Gaur0https://orcid.org/0000-0001-9750-4608Andrew Grieco1Yeshaiahu Fainman2Department of Electrical and Computer Engineering, University of California San Diego, La Jolla, CA, USAQualcomm Institute, University of California San Diego, La Jolla, CA, USADepartment of Electrical and Computer Engineering, University of California San Diego, La Jolla, CA, USAOptical coherence tomography is state-of-the-art in non-invasive imaging of biological structures. Spectral Domain Optical Coherence Tomography is the popularly used variation of this technique, but its performance is limited by the bandwidth and resolution of the system. In this work, we theoretically formulate the use of phase modulators and delay lines to act as filters on the tomography system and scan multiple channels. Various channels are then combined in a digital computer using filter bank theory to improve the sampling rate. The combination of multiple channels allows for increasing the axial resolution and maximum unambiguous range beyond the Nyquist limit. We then simulate the multirate spectral domain optical coherence tomography with 2 channels. We show that a single delay line can improve the axial resolution while a pair of phase modulators can improve the maximum unambiguous range of the system. We also show the use of multirate filter banks to carry out this process. Thus, by using a few extra components in the spectral domain optical coherence tomography, its performance can be increased manifold depending on the number of channels used. The extra cost is the time taken to perform the extra scans that is trivial for stationary objects like biological tissues.https://ieeexplore.ieee.org/document/10246288/Optical coherence tomographyfilter bank
spellingShingle Prabhav Gaur
Andrew Grieco
Yeshaiahu Fainman
Multirate Spectral Domain Optical Coherence Tomography
IEEE Photonics Journal
Optical coherence tomography
filter bank
title Multirate Spectral Domain Optical Coherence Tomography
title_full Multirate Spectral Domain Optical Coherence Tomography
title_fullStr Multirate Spectral Domain Optical Coherence Tomography
title_full_unstemmed Multirate Spectral Domain Optical Coherence Tomography
title_short Multirate Spectral Domain Optical Coherence Tomography
title_sort multirate spectral domain optical coherence tomography
topic Optical coherence tomography
filter bank
url https://ieeexplore.ieee.org/document/10246288/
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AT yeshaiahufainman multiratespectraldomainopticalcoherencetomography