Immunogenicity Assessment of Different Segments and Domains of Group A Streptococcal C5a Peptidase and Their Application Potential as Carrier Protein for Glycoconjugate Vaccine Development

Immunogenicity Assessment of Different Segments and Domains of Group A Streptococcal C5a Peptidase and Their Application Potential as Carrier Protein for Glycoconjugate Vaccine Development

Group A streptococcal C5a peptidase (ScpA) is a highly conserved surface virulence factor present on group A streptococcus (GAS) cell surfaces. It has attracted much more attention as a promising antigenic target for GAS vaccine development due to its high antigenicity to stimulate specific and immu...

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Bibliographic Details
Main Authors: Guirong Wang, Jielin Zhao, Yisheng Zhao, Subo Wang, Shaojie Feng, Guofeng Gu
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Vaccines
Subjects:
group A streptococcus
group A streptococcal C5a peptidase
subunit protein vaccine
immunogenicity
carrier protein
Online Access:https://www.mdpi.com/2076-393X/9/2/139

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