Epigenome-Wide Association Study of Prostate Cancer in African Americans Identifies DNA Methylation Biomarkers for Aggressive Disease

Epigenome-Wide Association Study of Prostate Cancer in African Americans Identifies DNA Methylation Biomarkers for Aggressive Disease

DNA methylation plays important roles in prostate cancer (PCa) development and progression. African American men have higher incidence and mortality rates of PCa than other racial groups in U.S. The goal of this study was to identify differentially methylated CpG sites and genes between clinically d...

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Bibliographic Details
Main Authors: Yifan Xu, Chia-Wen Tsai, Wen-Shin Chang, Yuyan Han, Maosheng Huang, Curtis A. Pettaway, Da-Tian Bau, Jian Gu
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Biomolecules
Subjects:
prostate cancer
African American
aggressive disease
DNA methylation
leukocytes
Online Access:https://www.mdpi.com/2218-273X/11/12/1826

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