MicroRNA Regulation of nAChR Expression and Nicotine-Dependent Behavior in C. elegans
Summary: Chronic exposure to nicotine upregulates nicotinic acetylcholine receptors (nAChRs), and such upregulation is critical for the development of nicotine dependence in humans and animal models. However, how nicotine upregulates nAChRs is not well understood. Here, we identify a key role for mi...
Main Authors: | Manish Rauthan, Jianke Gong, Jinzhi Liu, Zhaoyu Li, Seth A. Wescott, Jianfeng Liu, X.Z. Shawn Xu |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-11-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124717314900 |
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