Safety and Efficacy of Holmium Laser Enucleation of the Prostate (HoLEP) in Patients Requiring Anticoagulants/Antiplatelets: A Retrospective Study
Objective:We evaluated Holmium Laser Enucleation of the Prostate (HoLEP) surgery performed in patients with benign prostatic obstruction (BPO) requiring anticoagulant/antiplatelet (AC/AP) therapy in terms of safety and efficacy.Materials and Methods:The retrospective data of 250 patients who underwe...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2023-06-01
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| Series: | Journal of Urological Surgery |
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| Online Access: |
http://jurolsurgery.org/archives/archive-detail/article-preview/safety-and-efficacy-of-holmium-laser-enucleation-o/60534
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| _version_ | 1797809733002854400 |
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| author | Mehmet Yılmaz Onur Açıkgöz Halil Çağrı Aybal Kenan Yiğit Yıldız Eymen Gazel Lütfi Tunç |
| author_facet | Mehmet Yılmaz Onur Açıkgöz Halil Çağrı Aybal Kenan Yiğit Yıldız Eymen Gazel Lütfi Tunç |
| author_sort | Mehmet Yılmaz |
| collection | DOAJ |
| description | Objective:We evaluated Holmium Laser Enucleation of the Prostate (HoLEP) surgery performed in patients with benign prostatic obstruction (BPO) requiring anticoagulant/antiplatelet (AC/AP) therapy in terms of safety and efficacy.Materials and Methods:The retrospective data of 250 patients who underwent HoLEP between January 2020-May 2022 were included in the study. AC/AP treatment status’ of patients was recorded. The patients were divided into two groups as those requiring AC/AP (group 1, n=129) and those not using (group 2, n=121). Basic characteristics, preoperative and postoperative IPSS scores, Qmax and continence status’ at 1st and 6th month follow-up were recorded. Intra- and postoperative complications were recorded according to Clavien-Dindo classification.Results:No significant difference was observed between the groups in terms of preoeprative characteristics including prostate-specific antigen, hemoglobin (Hb), prostate volume, IPSS, Quality of Life score, Qmax, Qave and postvoiding residuel volume (p>0.05). There was no significant difference between the two groups in terms of postoperative functional parameters and urinary continence (p>0.05) and in Hb drop (0.13±0.1 g/dL vs. 0.08±0.15 g/dL, respectively; p=0.21). The blood transfusion rate was 2.3% in group 1 and 0.8% in group 2, and there was no significant difference between the groups (p=0.62). Additionally, there was no significant difference between the groups regarding complications.Conclusion:HoLEP is a safe and effective, minimally invasive surgical method that improves functional parameters in BPO patients requiring AC/AP. |
| first_indexed | 2024-03-13T06:57:11Z |
| format | Article |
| id | doaj.art-b34782e7d7e3489fbaddbad45e0c5475 |
| institution | Directory Open Access Journal |
| issn | 2148-9580 |
| language | English |
| last_indexed | 2024-03-13T06:57:11Z |
| publishDate | 2023-06-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Journal of Urological Surgery |
| spelling | doaj.art-b34782e7d7e3489fbaddbad45e0c54752023-06-07T06:57:08ZengGalenos YayineviJournal of Urological Surgery2148-95802023-06-0110210110610.4274/jus.galenos.2022.2022.006213049054Safety and Efficacy of Holmium Laser Enucleation of the Prostate (HoLEP) in Patients Requiring Anticoagulants/Antiplatelets: A Retrospective StudyMehmet Yılmaz0Onur Açıkgöz1Halil Çağrı Aybal2Kenan Yiğit Yıldız3Eymen Gazel4Lütfi Tunç5 Asklepios Clinic Triberg, Clinic of Urology, Triberg, Germany Pendik State Hospital, Clinic of Urology, Istanbul, Turkiye Ankara Polatlı Duatepe State Hospital, Clinic of Urology, Ankara, Turkiye Acıbadem Kocaeli Hospital, Clinic of Urology, Kocaeli, Turkiye Acıbadem University Ankara Hospital, Department of Urology, Ankara, Turkiye Gazi University Faculty of Medicine, Department of Urology, Ankara, Turkiye Objective:We evaluated Holmium Laser Enucleation of the Prostate (HoLEP) surgery performed in patients with benign prostatic obstruction (BPO) requiring anticoagulant/antiplatelet (AC/AP) therapy in terms of safety and efficacy.Materials and Methods:The retrospective data of 250 patients who underwent HoLEP between January 2020-May 2022 were included in the study. AC/AP treatment status’ of patients was recorded. The patients were divided into two groups as those requiring AC/AP (group 1, n=129) and those not using (group 2, n=121). Basic characteristics, preoperative and postoperative IPSS scores, Qmax and continence status’ at 1st and 6th month follow-up were recorded. Intra- and postoperative complications were recorded according to Clavien-Dindo classification.Results:No significant difference was observed between the groups in terms of preoeprative characteristics including prostate-specific antigen, hemoglobin (Hb), prostate volume, IPSS, Quality of Life score, Qmax, Qave and postvoiding residuel volume (p>0.05). There was no significant difference between the two groups in terms of postoperative functional parameters and urinary continence (p>0.05) and in Hb drop (0.13±0.1 g/dL vs. 0.08±0.15 g/dL, respectively; p=0.21). The blood transfusion rate was 2.3% in group 1 and 0.8% in group 2, and there was no significant difference between the groups (p=0.62). Additionally, there was no significant difference between the groups regarding complications.Conclusion:HoLEP is a safe and effective, minimally invasive surgical method that improves functional parameters in BPO patients requiring AC/AP. http://jurolsurgery.org/archives/archive-detail/article-preview/safety-and-efficacy-of-holmium-laser-enucleation-o/60534 anticoagulantbleedingholepsafety |
| spellingShingle | Mehmet Yılmaz Onur Açıkgöz Halil Çağrı Aybal Kenan Yiğit Yıldız Eymen Gazel Lütfi Tunç Safety and Efficacy of Holmium Laser Enucleation of the Prostate (HoLEP) in Patients Requiring Anticoagulants/Antiplatelets: A Retrospective Study Journal of Urological Surgery anticoagulant bleeding holep safety |
| title | Safety and Efficacy of Holmium Laser Enucleation of the Prostate (HoLEP) in Patients Requiring Anticoagulants/Antiplatelets: A Retrospective Study |
| title_full | Safety and Efficacy of Holmium Laser Enucleation of the Prostate (HoLEP) in Patients Requiring Anticoagulants/Antiplatelets: A Retrospective Study |
| title_fullStr | Safety and Efficacy of Holmium Laser Enucleation of the Prostate (HoLEP) in Patients Requiring Anticoagulants/Antiplatelets: A Retrospective Study |
| title_full_unstemmed | Safety and Efficacy of Holmium Laser Enucleation of the Prostate (HoLEP) in Patients Requiring Anticoagulants/Antiplatelets: A Retrospective Study |
| title_short | Safety and Efficacy of Holmium Laser Enucleation of the Prostate (HoLEP) in Patients Requiring Anticoagulants/Antiplatelets: A Retrospective Study |
| title_sort | safety and efficacy of holmium laser enucleation of the prostate holep in patients requiring anticoagulants antiplatelets a retrospective study |
| topic | anticoagulant bleeding holep safety |
| url |
http://jurolsurgery.org/archives/archive-detail/article-preview/safety-and-efficacy-of-holmium-laser-enucleation-o/60534
|
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