Regulation of NANOG and SOX2 expression by activin A and a canonical WNT agonist in bovine embryonic stem cells and blastocysts

Bovine embryonic stem cells (ESC) have features associated with the primed pluripotent state including low expression of one of the core pluripotency transcription factors, NANOG. It has been reported that NANOG expression can be upregulated in porcine ESC by treatment with activin A and the WNT ago...

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Bibliographic Details
Main Authors: Yao Xiao, Froylan Sosa, Pablo J. Ross, Kenneth E. Diffenderfer, Peter J. Hansen
Format: Article
Language:English
Published: The Company of Biologists 2021-11-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/10/11/bio058669