LncRNA NEAT1 promotes endometrial cancer cell proliferation, migration and invasion by regulating the miR-144-3p/EZH2 axis

Endometrial cancer (EC) is one of the most common gynaecological tumours in the worldwide. Long non-coding RNA (lncRNA) nuclear enriched abundant transcript 1 (NEAT1) promotes cell proliferation, migration and invasion in EC cells. However, the molecular mechanisms of NEAT1 in EC have not been fully...

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Main Authors: Wang Wei, Ge Liang, Xu Xiao-Juan, Yang Ting, Yuan Yue, Ma Xiao-Ling, Zhang Xue-Hong
Format: Article
Language:English
Published: Sciendo 2019-11-01
Series:Radiology and Oncology
Subjects:
Online Access:https://doi.org/10.2478/raon-2019-0051
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author Wang Wei
Ge Liang
Xu Xiao-Juan
Yang Ting
Yuan Yue
Ma Xiao-Ling
Zhang Xue-Hong
author_facet Wang Wei
Ge Liang
Xu Xiao-Juan
Yang Ting
Yuan Yue
Ma Xiao-Ling
Zhang Xue-Hong
author_sort Wang Wei
collection DOAJ
description Endometrial cancer (EC) is one of the most common gynaecological tumours in the worldwide. Long non-coding RNA (lncRNA) nuclear enriched abundant transcript 1 (NEAT1) promotes cell proliferation, migration and invasion in EC cells. However, the molecular mechanisms of NEAT1 in EC have not been fully clarified. We conducted this study to reveal the function of NEAT1 in EC tissues and cell lines.
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spelling doaj.art-b34a705e2cd34cc281fde5b46062cd122022-12-21T21:27:45ZengSciendoRadiology and Oncology1581-32072019-11-0153443444210.2478/raon-2019-0051raon-2019-0051LncRNA NEAT1 promotes endometrial cancer cell proliferation, migration and invasion by regulating the miR-144-3p/EZH2 axisWang Wei0Ge Liang1Xu Xiao-Juan2Yang Ting3Yuan Yue4Ma Xiao-Ling5Zhang Xue-Hong6The Reproductive Medicine Special Hospital of the 1st Hospital of Lanzhou University, Key Laboratory for Reproductive Medicine and Embryo, Lanzhou, Gansu Province, P. R. ChinaDepartment of Anesthesiology, Gansu Province Maternity and Child-care Hospital, Lanzhou, Gansu Province, P. R. ChinaThe Reproductive Medicine Special Hospital of the 1st Hospital of Lanzhou University, Key Laboratory for Reproductive Medicine and Embryo, Lanzhou, Gansu Province, P. R. ChinaThe Reproductive Medicine Special Hospital of the 1st Hospital of Lanzhou University, Key Laboratory for Reproductive Medicine and Embryo, Lanzhou, Gansu Province, P. R. ChinaThe Reproductive Medicine Special Hospital of the 1st Hospital of Lanzhou University, Key Laboratory for Reproductive Medicine and Embryo, Lanzhou, Gansu Province, P. R. ChinaThe Reproductive Medicine Special Hospital of the 1st Hospital of Lanzhou University, Key Laboratory for Reproductive Medicine and Embryo, Lanzhou, Gansu Province, P. R. ChinaThe Reproductive Medicine Special Hospital of the 1st Hospital of Lanzhou University, Key Laboratory for Reproductive Medicine and Embryo, Lanzhou, Gansu Province, P. R. ChinaEndometrial cancer (EC) is one of the most common gynaecological tumours in the worldwide. Long non-coding RNA (lncRNA) nuclear enriched abundant transcript 1 (NEAT1) promotes cell proliferation, migration and invasion in EC cells. However, the molecular mechanisms of NEAT1 in EC have not been fully clarified. We conducted this study to reveal the function of NEAT1 in EC tissues and cell lines.https://doi.org/10.2478/raon-2019-0051endometrial cancerneat1mir-144-3pezh2
spellingShingle Wang Wei
Ge Liang
Xu Xiao-Juan
Yang Ting
Yuan Yue
Ma Xiao-Ling
Zhang Xue-Hong
LncRNA NEAT1 promotes endometrial cancer cell proliferation, migration and invasion by regulating the miR-144-3p/EZH2 axis
Radiology and Oncology
endometrial cancer
neat1
mir-144-3p
ezh2
title LncRNA NEAT1 promotes endometrial cancer cell proliferation, migration and invasion by regulating the miR-144-3p/EZH2 axis
title_full LncRNA NEAT1 promotes endometrial cancer cell proliferation, migration and invasion by regulating the miR-144-3p/EZH2 axis
title_fullStr LncRNA NEAT1 promotes endometrial cancer cell proliferation, migration and invasion by regulating the miR-144-3p/EZH2 axis
title_full_unstemmed LncRNA NEAT1 promotes endometrial cancer cell proliferation, migration and invasion by regulating the miR-144-3p/EZH2 axis
title_short LncRNA NEAT1 promotes endometrial cancer cell proliferation, migration and invasion by regulating the miR-144-3p/EZH2 axis
title_sort lncrna neat1 promotes endometrial cancer cell proliferation migration and invasion by regulating the mir 144 3p ezh2 axis
topic endometrial cancer
neat1
mir-144-3p
ezh2
url https://doi.org/10.2478/raon-2019-0051
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AT yangting lncrnaneat1promotesendometrialcancercellproliferationmigrationandinvasionbyregulatingthemir1443pezh2axis
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