Impact of the First COVID-19 Wave on French Hospitalizations for Myocardial Infarction and Stroke: A Retrospective Cohort Study
The COVID-19 pandemic modified the management of myocardial infarction (MI) and stroke. We aimed to evaluate the effect of the COVID-19 pandemic on the volume and spatial distribution of hospitalizations for MI and stroke, before, during and after the first nationwide lockdown in France in 2020, com...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-10-01
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| Series: | Biomedicines |
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| Online Access: | https://www.mdpi.com/2227-9059/10/10/2501 |
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| author | Anne-Sophie Mariet Gauthier Duloquin Eric Benzenine Adrien Roussot Thibaut Pommier Jean-Christophe Eicher Laura Baptiste Maurice Giroud Yves Cottin Yannick Béjot Catherine Quantin |
| author_facet | Anne-Sophie Mariet Gauthier Duloquin Eric Benzenine Adrien Roussot Thibaut Pommier Jean-Christophe Eicher Laura Baptiste Maurice Giroud Yves Cottin Yannick Béjot Catherine Quantin |
| author_sort | Anne-Sophie Mariet |
| collection | DOAJ |
| description | The COVID-19 pandemic modified the management of myocardial infarction (MI) and stroke. We aimed to evaluate the effect of the COVID-19 pandemic on the volume and spatial distribution of hospitalizations for MI and stroke, before, during and after the first nationwide lockdown in France in 2020, compared with 2019. Hospitalization data were extracted from the French National Discharge database. Patient’s characteristics were compared according to COVID-19 status. Changes in hospitalization rates over time were measured using interrupted time series analysis. Possible spatial patterns of over or under-hospitalization rates were investigated using Moran’s indices. We observed a rapid and significant drop in hospitalizations just before the beginning of the lockdown with a nadir at 36.5% for MI and 31.2% for stroke. Hospitalization volumes returned to those seen in 2019 four weeks after the end of the lockdown, except for MI, which rebounded excessively. Older age, male sex, elevated rate of hypertension, diabetes, obesity and mortality characterized COVID-19 patients. There was no evidence of a change in the spatial pattern of over- or under-hospitalization clusters over the three periods. After a steep drop, only MI showed a significant rebound after the first lockdown with no change in the spatial distribution of hospitalizations. |
| first_indexed | 2024-03-09T20:39:13Z |
| format | Article |
| id | doaj.art-b34c5a9cd78e4da5b22043c5772fc526 |
| institution | Directory Open Access Journal |
| issn | 2227-9059 |
| language | English |
| last_indexed | 2024-03-09T20:39:13Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj.art-b34c5a9cd78e4da5b22043c5772fc5262023-11-23T23:04:04ZengMDPI AGBiomedicines2227-90592022-10-011010250110.3390/biomedicines10102501Impact of the First COVID-19 Wave on French Hospitalizations for Myocardial Infarction and Stroke: A Retrospective Cohort StudyAnne-Sophie Mariet0Gauthier Duloquin1Eric Benzenine2Adrien Roussot3Thibaut Pommier4Jean-Christophe Eicher5Laura Baptiste6Maurice Giroud7Yves Cottin8Yannick Béjot9Catherine Quantin10Biostatistics and Bioinformatics (DIM), University Hospital of Dijon, 21000 Dijon, FranceNeurology Department, University Hospital of Dijon, 21000 Dijon, FranceBiostatistics and Bioinformatics (DIM), University Hospital of Dijon, 21000 Dijon, FranceBiostatistics and Bioinformatics (DIM), University Hospital of Dijon, 21000 Dijon, FranceCardiology Department, University Hospital of Dijon, 21000 Dijon, FranceCardiology Department, University Hospital of Dijon, 21000 Dijon, FranceNeurology Department, University Hospital of Dijon, 21000 Dijon, FranceNeurology Department, University Hospital of Dijon, 21000 Dijon, FranceCardiology Department, University Hospital of Dijon, 21000 Dijon, FranceNeurology Department, University Hospital of Dijon, 21000 Dijon, FranceBiostatistics and Bioinformatics (DIM), University Hospital of Dijon, 21000 Dijon, FranceThe COVID-19 pandemic modified the management of myocardial infarction (MI) and stroke. We aimed to evaluate the effect of the COVID-19 pandemic on the volume and spatial distribution of hospitalizations for MI and stroke, before, during and after the first nationwide lockdown in France in 2020, compared with 2019. Hospitalization data were extracted from the French National Discharge database. Patient’s characteristics were compared according to COVID-19 status. Changes in hospitalization rates over time were measured using interrupted time series analysis. Possible spatial patterns of over or under-hospitalization rates were investigated using Moran’s indices. We observed a rapid and significant drop in hospitalizations just before the beginning of the lockdown with a nadir at 36.5% for MI and 31.2% for stroke. Hospitalization volumes returned to those seen in 2019 four weeks after the end of the lockdown, except for MI, which rebounded excessively. Older age, male sex, elevated rate of hypertension, diabetes, obesity and mortality characterized COVID-19 patients. There was no evidence of a change in the spatial pattern of over- or under-hospitalization clusters over the three periods. After a steep drop, only MI showed a significant rebound after the first lockdown with no change in the spatial distribution of hospitalizations.https://www.mdpi.com/2227-9059/10/10/2501stroketransient ischemic attackmyocardial infarctionCoronavirus Disease 2019lockdownspatial autocorrelation |
| spellingShingle | Anne-Sophie Mariet Gauthier Duloquin Eric Benzenine Adrien Roussot Thibaut Pommier Jean-Christophe Eicher Laura Baptiste Maurice Giroud Yves Cottin Yannick Béjot Catherine Quantin Impact of the First COVID-19 Wave on French Hospitalizations for Myocardial Infarction and Stroke: A Retrospective Cohort Study Biomedicines stroke transient ischemic attack myocardial infarction Coronavirus Disease 2019 lockdown spatial autocorrelation |
| title | Impact of the First COVID-19 Wave on French Hospitalizations for Myocardial Infarction and Stroke: A Retrospective Cohort Study |
| title_full | Impact of the First COVID-19 Wave on French Hospitalizations for Myocardial Infarction and Stroke: A Retrospective Cohort Study |
| title_fullStr | Impact of the First COVID-19 Wave on French Hospitalizations for Myocardial Infarction and Stroke: A Retrospective Cohort Study |
| title_full_unstemmed | Impact of the First COVID-19 Wave on French Hospitalizations for Myocardial Infarction and Stroke: A Retrospective Cohort Study |
| title_short | Impact of the First COVID-19 Wave on French Hospitalizations for Myocardial Infarction and Stroke: A Retrospective Cohort Study |
| title_sort | impact of the first covid 19 wave on french hospitalizations for myocardial infarction and stroke a retrospective cohort study |
| topic | stroke transient ischemic attack myocardial infarction Coronavirus Disease 2019 lockdown spatial autocorrelation |
| url | https://www.mdpi.com/2227-9059/10/10/2501 |
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