Zika virus infection: The resurgence of a neglected disease
"Zika virus" (ZIKV) is an enveloped, icosahedral virus and has a positive-sense, single-stranded RNA genome approximately 11 kb in length. Genetic studies have revealed three ZIKV lineages: East African, West African, and Asian. Serologic studies and virus isolations have demonstrated that...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2016-01-01
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| Series: | Medical Journal of Dr. D.Y. Patil University |
| Subjects: | |
| Online Access: | http://www.mjdrdypu.org/article.asp?issn=0975-2870;year=2016;volume=9;issue=2;spage=283;epage=287;aulast=Kambale |
| _version_ | 1819075710320377856 |
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| author | Tushar Kambale Banyameen Iqbal Sonali Salve Iqra Mushtaq |
| author_facet | Tushar Kambale Banyameen Iqbal Sonali Salve Iqra Mushtaq |
| author_sort | Tushar Kambale |
| collection | DOAJ |
| description | "Zika virus" (ZIKV) is an enveloped, icosahedral virus and has a positive-sense, single-stranded RNA genome approximately 11 kb in length. Genetic studies have revealed three ZIKV lineages: East African, West African, and Asian. Serologic studies and virus isolations have demonstrated that the virus has a wide geographic distribution, spanning East and West Africa, the Americas, Indian subcontinent, and Southeast Asia. ZIKV can cause complications such as Guillain-Barré syndrome, meningitis, meningoencephalitis, and myelitis. During pregnancy ZIKV infection can lead to miscarriages and microcephaly, cerebral calcifications, macular neuroretinal atrophy, and loss of foveal reflex in the fetus. A clinically suspected case of infection with dengue negative result should be further tested for Flavivirus, including Zika. Immunofluorescence or enzyme-linked immunosorbent assay is used to detect specific IgM or IgG antibodies against ZIKV. In cases of positive ZIKV infection, symptomatic treatment should be given after excluding other condition such as dengue, malaria, and bacterial infections. |
| first_indexed | 2024-12-21T18:29:44Z |
| format | Article |
| id | doaj.art-b34e50ef8f1645f8a911344d2fb5ccee |
| institution | Directory Open Access Journal |
| issn | 0975-2870 |
| language | English |
| last_indexed | 2024-12-21T18:29:44Z |
| publishDate | 2016-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Medical Journal of Dr. D.Y. Patil University |
| spelling | doaj.art-b34e50ef8f1645f8a911344d2fb5ccee2022-12-21T18:54:18ZengWolters Kluwer Medknow PublicationsMedical Journal of Dr. D.Y. Patil University0975-28702016-01-019228328710.4103/0975-2870.177699Zika virus infection: The resurgence of a neglected diseaseTushar KambaleBanyameen IqbalSonali SalveIqra Mushtaq"Zika virus" (ZIKV) is an enveloped, icosahedral virus and has a positive-sense, single-stranded RNA genome approximately 11 kb in length. Genetic studies have revealed three ZIKV lineages: East African, West African, and Asian. Serologic studies and virus isolations have demonstrated that the virus has a wide geographic distribution, spanning East and West Africa, the Americas, Indian subcontinent, and Southeast Asia. ZIKV can cause complications such as Guillain-Barré syndrome, meningitis, meningoencephalitis, and myelitis. During pregnancy ZIKV infection can lead to miscarriages and microcephaly, cerebral calcifications, macular neuroretinal atrophy, and loss of foveal reflex in the fetus. A clinically suspected case of infection with dengue negative result should be further tested for Flavivirus, including Zika. Immunofluorescence or enzyme-linked immunosorbent assay is used to detect specific IgM or IgG antibodies against ZIKV. In cases of positive ZIKV infection, symptomatic treatment should be given after excluding other condition such as dengue, malaria, and bacterial infections.http://www.mjdrdypu.org/article.asp?issn=0975-2870;year=2016;volume=9;issue=2;spage=283;epage=287;aulast=KambaleAedes aegyptiFlavivirusZika virus |
| spellingShingle | Tushar Kambale Banyameen Iqbal Sonali Salve Iqra Mushtaq Zika virus infection: The resurgence of a neglected disease Medical Journal of Dr. D.Y. Patil University Aedes aegypti Flavivirus Zika virus |
| title | Zika virus infection: The resurgence of a neglected disease |
| title_full | Zika virus infection: The resurgence of a neglected disease |
| title_fullStr | Zika virus infection: The resurgence of a neglected disease |
| title_full_unstemmed | Zika virus infection: The resurgence of a neglected disease |
| title_short | Zika virus infection: The resurgence of a neglected disease |
| title_sort | zika virus infection the resurgence of a neglected disease |
| topic | Aedes aegypti Flavivirus Zika virus |
| url | http://www.mjdrdypu.org/article.asp?issn=0975-2870;year=2016;volume=9;issue=2;spage=283;epage=287;aulast=Kambale |
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