The anti-tumor effect of proteasome inhibitor MG132 for human adenoid cystic carcinoma: correlate with the emerging role of Nrf2/Keap1 signaling pathway

The anti-tumor effect of proteasome inhibitor MG132 for human adenoid cystic carcinoma: correlate with the emerging role of Nrf2/Keap1 signaling pathway

Abstract Background Adenoid cystic carcinoma (ACC) is one of the most common malignant salivary gland tumors. Moreover, the unique biological characteristics and complex structures of ACC contribute to its poor survival rates. Recently, proteasome inhibitors have been shown to elicit satisfactory th...

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Bibliographic Details
Main Authors: Jiazhi Xu, Haiwei Wu, Jiatong Sun, Zhiyuan Gong, Xiaoya Lu, Enli Yang, Zhanwei Chen, Shengyun Huang, Xiaolin Nong, Dongsheng Zhang
Format: Article
Language:English
Published: BMC 2022-05-01
Series:Head & Face Medicine
Subjects:
Adenoid cystic carcinoma
Proteasome inhibitor
MG132
Nrf2/Keap1
Apoptosis
Online Access:https://doi.org/10.1186/s13005-022-00318-1

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