Homing of vertebral‐delivered mesenchymal stromal cells for degenerative intervertebral discs repair – an in vivo proof‐of‐concept study

Homing of vertebral‐delivered mesenchymal stromal cells for degenerative intervertebral discs repair – an in vivo proof‐of‐concept study

Abstract Introduction Cell transplantation shows promising results for intervertebral disc (IVD) repair, however, contemporary strategies present concerns regarding needle puncture damage, cell retention, and straining the limited nutrient availability. Mesenchymal stromal cell (MSC) homing is a nat...

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Bibliographic Details
Main Authors: Jordy Schol, Daisuke Sakai, Takayuki Warita, Tadashi Nukaga, Kosuke Sako, Sebastian Wangler, Shota Tamagawa, Stephan Zeiter, Mauro Alini, Sibylle Grad
Format: Article
Language:English
Published: Wiley 2023-03-01
Series:JOR Spine
Subjects:
cell therapy
degeneration
homing
intervertebral disc
mesenchymal stromal cells
rat model
Online Access:https://doi.org/10.1002/jsp2.1228

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