Structural and dynamic mechanisms for coupled folding and tRNA recognition of a translational T-box riboswitch
Abstract T-box riboswitches are unique riboregulators where gene regulation is mediated through interactions between two highly structured RNAs. Despite extensive structural insights, how RNA-RNA interactions drive the folding and structural transitions of T-box to achieve functional conformations r...
Main Authors: | Xiaolin Niu, Zhonghe Xu, Yufan Zhang, Xiaobing Zuo, Chunlai Chen, Xianyang Fang |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-11-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-43232-z |
Similar Items
-
Translational T-box riboswitches bind tRNA by modulating conformational flexibility
by: Eduardo Campos-Chavez, et al.
Published: (2024-08-01) -
tRNA Fusion to Streamline RNA Structure Determination: Case Studies in Probing Aminoacyl-tRNA Sensing Mechanisms by the T-Box Riboswitch
by: Jason C. Grigg, et al.
Published: (2022-05-01) -
Specific structural elements of the T-box riboswitch drive the two-step binding of the tRNA ligand
by: Jiacheng Zhang, et al.
Published: (2018-09-01) -
RNA folding kinetics control riboswitch sensitivity in vivo
by: David Z. Bushhouse, et al.
Published: (2025-01-01) -
Structural basis of tRNA recognition by the widespread OB fold
by: Aline Umuhire Juru, et al.
Published: (2024-07-01)