Effects of dietary turmeric (Curcuma longa) on innate and acquired immune responses in broiler chicken
One of the most desired treatments to combat stress and inflammation with minimal adverse effects in large bird populations is food additives. This study investigated the effects of dietary turmeric (Curcuma longa) on the level of serum amyloid A (SAA) as an indicator for acute phase response and an...
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| Format: | Article |
| Language: | English |
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Elsevier
2021-12-01
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| Series: | Veterinary and Animal Science |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2451943X2100048X |
| _version_ | 1819101901452476416 |
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| author | Meysam Khodadadi Nariman Sheikhi Hadi Haghbin Nazarpak Gholamreza Nikbakht Brujeni |
| author_facet | Meysam Khodadadi Nariman Sheikhi Hadi Haghbin Nazarpak Gholamreza Nikbakht Brujeni |
| author_sort | Meysam Khodadadi |
| collection | DOAJ |
| description | One of the most desired treatments to combat stress and inflammation with minimal adverse effects in large bird populations is food additives. This study investigated the effects of dietary turmeric (Curcuma longa) on the level of serum amyloid A (SAA) as an indicator for acute phase response and antibody titer to Newcastle vaccine as an indicator for humoral immune response. A total of 300 Ross broiler chickens were assigned to five dietary groups. Two treatments received basal diets supplemented with different amount of turmeric (250 and 500 mg/kg). One group received aspirin (ASA; 250 mg/L) and one group aspirin-vitamin C (ASA; 250 mg/L + Ascorbic acid; 20 mg/L) in drinking water. There was one control group that received no feeding additives. The levels of SAA and humoral antibody response to Newcastle vaccine were measured during the entire production period. Turmeric administration significantly decreased the serum SAA concentrations after 2 weeks of treatment and later. It also significantly reduced SAA elevation due to the vaccinations on day 17 but not on day 28. After the second vaccination (d 19) ELISA titer in all treatment groups was higher than control group. Significant effect of dietary turmeric on body weight was also found at week 3 and later ages. Administration of 250 mg turmeric per kg diet is recommended for broiler chickens. It is concluded that turmeric is beneficial to minimize inflammatory effects of vaccination in commercial broiler chickens. Turmeric prevents and reduces stress and negative effects of inflammation and stimulates growth performance of broiler chickens. |
| first_indexed | 2024-12-22T01:26:02Z |
| format | Article |
| id | doaj.art-b35747d50f6a48a6a0b6c357d810b90c |
| institution | Directory Open Access Journal |
| issn | 2451-943X |
| language | English |
| last_indexed | 2024-12-22T01:26:02Z |
| publishDate | 2021-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Veterinary and Animal Science |
| spelling | doaj.art-b35747d50f6a48a6a0b6c357d810b90c2022-12-21T18:43:36ZengElsevierVeterinary and Animal Science2451-943X2021-12-0114100213Effects of dietary turmeric (Curcuma longa) on innate and acquired immune responses in broiler chickenMeysam Khodadadi0Nariman Sheikhi1Hadi Haghbin Nazarpak2Gholamreza Nikbakht Brujeni3Department of Clinical Science, Faculty of Veterinary Medicine, Science and Research Branch, Islamic Azad University, Tehran, IranDepartment of Clinical Science, Faculty of Veterinary Medicine, Science and Research Branch, Islamic Azad University, Tehran, IranDepartment of Clinical Sciences, Faculty of Veterinary Medicine, Garmsar Branch, Islamic Azad University, Garmsar, IranDepartment of Microbiology and immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran; Corresponding author at : Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Azadi Avenue, Tehran, IranOne of the most desired treatments to combat stress and inflammation with minimal adverse effects in large bird populations is food additives. This study investigated the effects of dietary turmeric (Curcuma longa) on the level of serum amyloid A (SAA) as an indicator for acute phase response and antibody titer to Newcastle vaccine as an indicator for humoral immune response. A total of 300 Ross broiler chickens were assigned to five dietary groups. Two treatments received basal diets supplemented with different amount of turmeric (250 and 500 mg/kg). One group received aspirin (ASA; 250 mg/L) and one group aspirin-vitamin C (ASA; 250 mg/L + Ascorbic acid; 20 mg/L) in drinking water. There was one control group that received no feeding additives. The levels of SAA and humoral antibody response to Newcastle vaccine were measured during the entire production period. Turmeric administration significantly decreased the serum SAA concentrations after 2 weeks of treatment and later. It also significantly reduced SAA elevation due to the vaccinations on day 17 but not on day 28. After the second vaccination (d 19) ELISA titer in all treatment groups was higher than control group. Significant effect of dietary turmeric on body weight was also found at week 3 and later ages. Administration of 250 mg turmeric per kg diet is recommended for broiler chickens. It is concluded that turmeric is beneficial to minimize inflammatory effects of vaccination in commercial broiler chickens. Turmeric prevents and reduces stress and negative effects of inflammation and stimulates growth performance of broiler chickens.http://www.sciencedirect.com/science/article/pii/S2451943X2100048XTurmericAcute phase responseSerum amyloid aChicken |
| spellingShingle | Meysam Khodadadi Nariman Sheikhi Hadi Haghbin Nazarpak Gholamreza Nikbakht Brujeni Effects of dietary turmeric (Curcuma longa) on innate and acquired immune responses in broiler chicken Veterinary and Animal Science Turmeric Acute phase response Serum amyloid a Chicken |
| title | Effects of dietary turmeric (Curcuma longa) on innate and acquired immune responses in broiler chicken |
| title_full | Effects of dietary turmeric (Curcuma longa) on innate and acquired immune responses in broiler chicken |
| title_fullStr | Effects of dietary turmeric (Curcuma longa) on innate and acquired immune responses in broiler chicken |
| title_full_unstemmed | Effects of dietary turmeric (Curcuma longa) on innate and acquired immune responses in broiler chicken |
| title_short | Effects of dietary turmeric (Curcuma longa) on innate and acquired immune responses in broiler chicken |
| title_sort | effects of dietary turmeric curcuma longa on innate and acquired immune responses in broiler chicken |
| topic | Turmeric Acute phase response Serum amyloid a Chicken |
| url | http://www.sciencedirect.com/science/article/pii/S2451943X2100048X |
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