Association of ERAP1 and ERAP2 gene polymorphisms and ERAP2 protein with the susceptibility and severity of rheumatoid arthritis in the Ukrainian population

Association of ERAP1 and ERAP2 gene polymorphisms and ERAP2 protein with the susceptibility and severity of rheumatoid arthritis in the Ukrainian population

IntroductionRheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints. Although RA is chiefly associated with HLA class II, nevertheless some HLA class I associations have also been observed. These molecules present antigenic peptides to CD8+ T lymphocytes and natura...

書目詳細資料
Main Authors:	Iryna Kril, Andrzej Wiśniewski, Agnieszka Tarnowska, Khrystyna Lishchuk-Yakymovych, Yaryna Bojko, Piotr Kuśnierczyk, Valentyna V. Chopyak, Izabela Nowak
格式:	Article
語言:	English
出版:	Frontiers Media S.A. 2025-01-01
叢編:	Frontiers in Immunology
主題:	rheumatoid arthritis MHC I class ERAP1 ERAP2 single nucleotide polymorphisms
在線閱讀:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1519159/full

相似書籍

Polymorphisms in ERAP1 and ERAP2 Genes Are Associated With Tuberculosis in the Han Chinese
由: Shuqiong Zhang, et al.
出版: (2020-11-01)

The important roles of ERAP1, ERAP2 genes polymorphisms and their DNA methylation levels in pulmonary tuberculosis
由: Shi-Hong Su, et al.
出版: (2025-02-01)

The Multifaceted Nature of Aminopeptidases ERAP1, ERAP2, and LNPEP: From Evolution to Disease
由: Fabiana Paladini, et al.
出版: (2020-07-01)

Impact of endoplasmic reticulum aminopeptidases 1 (ERAP1) and 2 (ERAP2) on neutrophil cellular functions
由: Irma Saulle, et al.
出版: (2025-01-01)

The emerging multifunctional roles of ERAP1, ERAP2 and IRAP between antigen processing and renin-angiotensin system modulation
由: Benedetta Mattorre, et al.
出版: (2022-09-01)

How ERAP1 and ERAP2 Shape the Peptidomes of Disease-Associated MHC-I Proteins
由: José A. López de Castro
出版: (2018-10-01)

An Overview on ERAP Roles in Infectious Diseases
由: Irma Saulle, et al.
出版: (2020-03-01)

Expression and role of ERAP1 in placental tissues of preeclampsia
由: Yanyan Xu, et al.
出版: (2020-04-01)

ERAP, KIR, and HLA-C Profile in Recurrent Implantation Failure
由: Karolina Piekarska, et al.
出版: (2021-10-01)

The Role of Aminopeptidase ERAP1 in Human Pathology—A Review
由: Laura Țiburcă, et al.
出版: (2024-02-01)

The effect of rs2910686 on ERAP2 expression in IBD and epithelial inflammatory response
由: Siri Sæterstad, et al.
出版: (2024-08-01)

ERAP1 Gene Variants and Haplotypes Associated With Psoriasis Vulgaris of Han Chinese in Inner Mongolia
由: Xin Li, et al.
出版: (2024-11-01)

A cis-regulatory element regulates ERAP2 expression through autoimmune disease risk SNPs
由: Wouter J. Venema, et al.
出版: (2024-01-01)

ERAP2 Increases the Abundance of a Peptide Submotif Highly Selective for the Birdshot Uveitis-Associated HLA-A29
由: Wouter J. Venema, et al.
出版: (2021-02-01)

ERAP2 Is Associated With Immune Infiltration and Predicts Favorable Prognosis in SqCLC
由: Zhenlin Yang, et al.
出版: (2021-12-01)

Combining ERAP1 silencing and entinostat therapy to overcome resistance to cancer immunotherapy in neuroblastoma
由: Patrizia Tempora, et al.
出版: (2024-10-01)

Down-regulation of ERAP1 mRNA expression in non-small cell lung cancer
由: Marta Wagner, et al.
出版: (2023-04-01)

Endoplasmic Reticulum Associated Aminopeptidase 2 (ERAP2) Is Released in the Secretome of Activated MDMs and Reduces in vitro HIV-1 Infection
由: Irma Saulle, et al.
出版: (2019-07-01)

THE ASSOCIATION OF ERAP2 GENE POLYMORPHISMS WITH SERONEGATIVE SPONDYLOARTHROPATHIES IN HLA-B27 NEGATIVE ROMANIANS
由: Laura Ioana Cherciu, et al.
出版: (2016-06-01)

A New ERAP2/Iso3 Isoform Expression Is Triggered by Different Microbial Stimuli in Human Cells. Could It Play a Role in the Modulation of SARS-CoV-2 Infection?
由: Irma Saulle, et al.
出版: (2020-08-01)

Ankylosing Spondylitis: A Trade Off of HLA-B27, ERAP, and Pathogen Interconnections? Focus on Sardinia
由: Fabiana Paladini, et al.
出版: (2019-01-01)

Association of <i>ERAP1</i> and <i>IL23R</i> gene polymorphisms with ankylosing spondylitis
由: U. A. Yakubova, et al.
出版: (2020-09-01)

Functional <i>ERAP1</i> Variants Distinctively Associate with Ankylosing Spondylitis Susceptibility under the Influence of <i>HLA-B27</i> in Taiwanese
由: Chin-Man Wang, et al.
出版: (2022-08-01)

To Be or Not to Be: The Case of Endoplasmic Reticulum Aminopeptidase 2
由: Piotr Kuśnierczyk
出版: (2022-06-01)

ERAP1 overexpression in HPV-induced malignancies: A possible novel immune evasion mechanism
由: Alina Steinbach, et al.
出版: (2017-07-01)

ERAP1 Controls the Interaction of the Inhibitory Receptor KIR3DL1 With HLA-B51:01 by Affecting Natural Killer Cell Function
由: Silvia D’Amico, et al.
出版: (2021-11-01)

Multifactor dimensionality reduction reveals the effect of interaction between ERAP1 and IFIH1 polymorphisms in psoriasis susceptibility genes
由: Chang Zhang, et al.
出版: (2022-11-01)

Polymorphisms of Antigen-Presenting Machinery Genes in Non-Small Cell Lung Cancer: Different Impact on Disease Risk and Clinical Parameters in Smokers and Never-Smokers
由: Andrzej Wiśniewski, et al.
出版: (2021-05-01)

Editorial: Insights in antigen presenting cell biology: 2021
由: Peter van Endert, et al.
出版: (2022-11-01)

The Role of Conformational Dynamics in Antigen Trimming by Intracellular Aminopeptidases
由: Athanasios Papakyriakou, et al.
出版: (2017-08-01)

The ER Aminopeptidases, ERAP1 and ERAP2, synergize to self-modulate their respective activities
由: Adrian Martín-Esteban, et al.
出版: (2022-12-01)

Genetic association of ERAP1 and ERAP2 with eclampsia and preeclampsia in northeastern Brazilian women
由: Leonardo Capistrano Ferreira, et al.
出版: (2021-03-01)

The Differential Expression of ERAP1/ERAP2 and Immune Cell Activation in Pre-eclampsia
由: Kimberly Seamon, et al.
出版: (2020-03-01)

Can ERAP1 and ERAP2 Form Functional Heterodimers? A Structural Dynamics Investigation
由: Athanasios Papakyriakou, et al.
出版: (2022-04-01)

ERAP1 and ankylosing spondylitis.
由: Keidel, S, et al.
出版: (2013)

ERAP1 inhibitor development
由: Guzanov, P
出版: (2017)

Endoplasmic reticulum aminopeptidase-1 polymorphism increases the risk of rheumatoid arthritis
由: Akbulut Ekrem, et al.
出版: (2022-03-01)

Genetic variants in ERAP1 and ERAP2 associated with immune-mediated diseases influence protein expression and the isoform profile
由: Hanson, A, et al.
出版: (2017)

Concerted in vitro trimming of viral HLA-B27-restricted ligands by human ERAP1 and ERAP2 aminopeptidases.
由: Elena Lorente, et al.
出版: (2013-01-01)

Endoplasmic reticulum aminopeptidase 2 regulates CD4+ T cells pyroptosis in rheumatoid arthritis
由: Jianhua Zhang, et al.
出版: (2024-01-01)