Association of ERAP1 and ERAP2 gene polymorphisms and ERAP2 protein with the susceptibility and severity of rheumatoid arthritis in the Ukrainian population

Association of ERAP1 and ERAP2 gene polymorphisms and ERAP2 protein with the susceptibility and severity of rheumatoid arthritis in the Ukrainian population

IntroductionRheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints. Although RA is chiefly associated with HLA class II, nevertheless some HLA class I associations have also been observed. These molecules present antigenic peptides to CD8+ T lymphocytes and natura...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Iryna Kril, Andrzej Wiśniewski, Agnieszka Tarnowska, Khrystyna Lishchuk-Yakymovych, Yaryna Bojko, Piotr Kuśnierczyk, Valentyna V. Chopyak, Izabela Nowak
स्वरूप: लेख
भाषा:English
प्रकाशित: Frontiers Media S.A. 2025-01-01
श्रृंखला:Frontiers in Immunology
विषय:
rheumatoid arthritis
MHC I class
ERAP1
ERAP2
single nucleotide polymorphisms
ऑनलाइन पहुंच:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1519159/full

इंटरनेट

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1519159/full

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