Targeting MAPK Pathways by Naringenin Modulates Microglia M1/M2 Polarization in Lipopolysaccharide-Stimulated Cultures

Targeting MAPK Pathways by Naringenin Modulates Microglia M1/M2 Polarization in Lipopolysaccharide-Stimulated Cultures

Neuroinflammation is considered to be an important and inevitable pathological process associated with all types of damages to, and disorders of, the central nervous system. The hallmark of neuroinflammation is the microglia activation. In response to different micro-environmental disturbances, micr...

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Bibliographic Details
Main Authors: Bei Zhang, Yi-Zheng Wei, Guo-Qing Wang, Dai-Di Li, Jing-Shan Shi, Feng Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Cellular Neuroscience
Subjects:
neuroinflammation
microglia polarization
lipopolysaccharide
naringenin
MAPK signaling
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00531/full

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