Pulmonary Nodule Detection from X-ray CT Images Based on Region Shape Analysis and Appearance-based Clustering

In this paper, we propose a detection method of pulmonary nodules in X-ray computed tomography (CT) scans by use of three image filters and appearance-based k-means clustering. First, voxel values are suppressed in radial directions so as to eliminate extra regions in the volumes of interest (VOIs)....

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Main Authors: Takanobu Yanagihara, Hotaka Takizawa
Format: Article
Language:English
Published: MDPI AG 2015-05-01
Series:Algorithms
Subjects:
Online Access:http://www.mdpi.com/1999-4893/8/2/209
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author Takanobu Yanagihara
Hotaka Takizawa
author_facet Takanobu Yanagihara
Hotaka Takizawa
author_sort Takanobu Yanagihara
collection DOAJ
description In this paper, we propose a detection method of pulmonary nodules in X-ray computed tomography (CT) scans by use of three image filters and appearance-based k-means clustering. First, voxel values are suppressed in radial directions so as to eliminate extra regions in the volumes of interest (VOIs). Globular regions are enhanced by moment-of-inertia tensors where the voxel values in the VOIs are regarded as mass. Excessively enhanced voxels are reduced based on displacement between the VOI centers and the gravity points of the voxel values in the VOIs. Initial nodule candidates are determined by these filtering processings. False positives are reduced by, first, normalizing the directions of intensity distributions in the VOIs by rotating the VOIs based on the eigenvectors of the moment-of-inertia tensors, and then applying an appearance-based two-step k-means clustering technique to the rotated VOIs. The proposed method is applied to actual CT scans and experimental results are shown.
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spelling doaj.art-b35dd57816d442429216ad4e480072d42022-12-22T00:11:04ZengMDPI AGAlgorithms1999-48932015-05-018220922310.3390/a8020209a8020209Pulmonary Nodule Detection from X-ray CT Images Based on Region Shape Analysis and Appearance-based ClusteringTakanobu Yanagihara0Hotaka Takizawa1Graduate School of Systems and Information Engineering, University of Tsukuba, 305-8573, JapanFaculty of Engineering, Information and Systems, University of Tsukuba, 305-8573, JapanIn this paper, we propose a detection method of pulmonary nodules in X-ray computed tomography (CT) scans by use of three image filters and appearance-based k-means clustering. First, voxel values are suppressed in radial directions so as to eliminate extra regions in the volumes of interest (VOIs). Globular regions are enhanced by moment-of-inertia tensors where the voxel values in the VOIs are regarded as mass. Excessively enhanced voxels are reduced based on displacement between the VOI centers and the gravity points of the voxel values in the VOIs. Initial nodule candidates are determined by these filtering processings. False positives are reduced by, first, normalizing the directions of intensity distributions in the VOIs by rotating the VOIs based on the eigenvectors of the moment-of-inertia tensors, and then applying an appearance-based two-step k-means clustering technique to the rotated VOIs. The proposed method is applied to actual CT scans and experimental results are shown.http://www.mdpi.com/1999-4893/8/2/209chest X-ray computed tomography (CT) scansdetection of pulmonary nodulesmoment-of-inertiaappearance-based k-means clustering
spellingShingle Takanobu Yanagihara
Hotaka Takizawa
Pulmonary Nodule Detection from X-ray CT Images Based on Region Shape Analysis and Appearance-based Clustering
Algorithms
chest X-ray computed tomography (CT) scans
detection of pulmonary nodules
moment-of-inertia
appearance-based k-means clustering
title Pulmonary Nodule Detection from X-ray CT Images Based on Region Shape Analysis and Appearance-based Clustering
title_full Pulmonary Nodule Detection from X-ray CT Images Based on Region Shape Analysis and Appearance-based Clustering
title_fullStr Pulmonary Nodule Detection from X-ray CT Images Based on Region Shape Analysis and Appearance-based Clustering
title_full_unstemmed Pulmonary Nodule Detection from X-ray CT Images Based on Region Shape Analysis and Appearance-based Clustering
title_short Pulmonary Nodule Detection from X-ray CT Images Based on Region Shape Analysis and Appearance-based Clustering
title_sort pulmonary nodule detection from x ray ct images based on region shape analysis and appearance based clustering
topic chest X-ray computed tomography (CT) scans
detection of pulmonary nodules
moment-of-inertia
appearance-based k-means clustering
url http://www.mdpi.com/1999-4893/8/2/209
work_keys_str_mv AT takanobuyanagihara pulmonarynoduledetectionfromxrayctimagesbasedonregionshapeanalysisandappearancebasedclustering
AT hotakatakizawa pulmonarynoduledetectionfromxrayctimagesbasedonregionshapeanalysisandappearancebasedclustering