Systematic review of NTRK 1/2/3 fusion prevalence pan-cancer and across solid tumours

Abstract NTRK gene fusions are rare somatic mutations found across cancer types with promising targeted therapies emerging. Healthcare systems face significant challenges in integrating these treatments, with uncertainty in prevalence and optimal testing methods to identify eligible patients. We per...

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Hlavní autoři: Sophie O’Haire, Fanny Franchini, Yoon-Jung Kang, Julia Steinberg, Karen Canfell, Jayesh Desai, Stephen Fox, Maarten IJzerman
Médium: Článek
Jazyk:English
Vydáno: Nature Portfolio 2023-03-01
Edice:Scientific Reports
On-line přístup:https://doi.org/10.1038/s41598-023-31055-3