Systematic review of NTRK 1/2/3 fusion prevalence pan-cancer and across solid tumours

Abstract NTRK gene fusions are rare somatic mutations found across cancer types with promising targeted therapies emerging. Healthcare systems face significant challenges in integrating these treatments, with uncertainty in prevalence and optimal testing methods to identify eligible patients. We per...

Полное описание

Библиографические подробности
Главные авторы: Sophie O’Haire, Fanny Franchini, Yoon-Jung Kang, Julia Steinberg, Karen Canfell, Jayesh Desai, Stephen Fox, Maarten IJzerman
Формат: Статья
Язык:English
Опубликовано: Nature Portfolio 2023-03-01
Серии:Scientific Reports
Online-ссылка:https://doi.org/10.1038/s41598-023-31055-3