Psychosis in children of separated parents: A systematic review and meta-analysis
AbstractBackground.Parental separation is a very common childhood adversity. The association between other adverse childhood experiences and an increased risk of psychosis has been reported. However, the evidence on the risk of psychosis for children of separated parents is limited. In this systemat...
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2020-01-01
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| Series: | European Psychiatry |
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| Online Access: | https://www.cambridge.org/core/product/identifier/S0924933819000154/type/journal_article |
| _version_ | 1811156327706132480 |
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| author | Luis Ayerbe María Pérez-Piñar Quintí Foguet-Boreu Salma Ayis |
| author_facet | Luis Ayerbe María Pérez-Piñar Quintí Foguet-Boreu Salma Ayis |
| author_sort | Luis Ayerbe |
| collection | DOAJ |
| description | AbstractBackground.Parental separation is a very common childhood adversity. The association between other adverse childhood experiences and an increased risk of psychosis has been reported. However, the evidence on the risk of psychosis for children of separated parents is limited. In this systematic review, cohort, case–control, and cross-sectional studies, comparing the risk of psychotic disorders for people with and without separated parents, were searched, critically appraised, and summarized.Methods.Studies were searched in PubMed, EMBASE, PsycINFO, and the Web of Science, from database inception to September 2019. A meta-analysis, using random-effects models, was undertaken to obtain pooled estimates of the risk of psychosis among participants with separated parents.Results.Twelve studies, with 305,652 participants from 22 countries, were included in the review. A significantly increased risk of psychosis for those with separated parents was observed, with a pooled odds ratio: 1.53 (95% confidence interval [CI]: 1.29–1.76), p < 0.001. The association remained significant when cohort, case–control, and cross-sectional studies were analyzed separately. The five cohort studies included in this review showed and increased risk of psychosis with odds ratio: 1.47 (95% CI: 1.26–1.69), p < 0.001.Conclusions.Parental separation is a common childhood adversity associated with an increased risk of psychosis. Although the risk for an individual child of separated parents is still low, given the high proportion of couple that separate, the increased rates of psychosis may be substantial in the population. Further studies on the risk of psychosis in those with separated parents, and the explanatory factors for this association, are required. |
| first_indexed | 2024-04-10T04:49:38Z |
| format | Article |
| id | doaj.art-b3604962f010408aad25f1d5246ded7b |
| institution | Directory Open Access Journal |
| issn | 0924-9338 1778-3585 |
| language | English |
| last_indexed | 2024-04-10T04:49:38Z |
| publishDate | 2020-01-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | European Psychiatry |
| spelling | doaj.art-b3604962f010408aad25f1d5246ded7b2023-03-09T12:33:57ZengCambridge University PressEuropean Psychiatry0924-93381778-35852020-01-016310.1192/j.eurpsy.2019.15Psychosis in children of separated parents: A systematic review and meta-analysisLuis Ayerbe0María Pérez-Piñar1Quintí Foguet-Boreu2Salma Ayis3Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom Centre of Primary Care and Public Health, Queen Mary University of London, London, United Kingdom Carnarvon Medical Centre, Southend-on-Sea, United KingdomCarnarvon Medical Centre, Southend-on-Sea, United KingdomDepartment of Psychiatry, Vic University Hospital, Vic, Spain Faculty of Health Sciences and Welfare, University of Vic-Central University of Catalonia (UVic-UCC), Vic, SpainSchool of Population Health and Environmental Sciences, King’s College London, London, United Kingdom National Institute for Health Research Biomedical Research Centre, Guy’s and St Thomas’ NHS Foundation Trust, London, United Kingdom National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care, South London at King’s College Hospital NHS Foundation Trust, London, United KingdomAbstractBackground.Parental separation is a very common childhood adversity. The association between other adverse childhood experiences and an increased risk of psychosis has been reported. However, the evidence on the risk of psychosis for children of separated parents is limited. In this systematic review, cohort, case–control, and cross-sectional studies, comparing the risk of psychotic disorders for people with and without separated parents, were searched, critically appraised, and summarized.Methods.Studies were searched in PubMed, EMBASE, PsycINFO, and the Web of Science, from database inception to September 2019. A meta-analysis, using random-effects models, was undertaken to obtain pooled estimates of the risk of psychosis among participants with separated parents.Results.Twelve studies, with 305,652 participants from 22 countries, were included in the review. A significantly increased risk of psychosis for those with separated parents was observed, with a pooled odds ratio: 1.53 (95% confidence interval [CI]: 1.29–1.76), p < 0.001. The association remained significant when cohort, case–control, and cross-sectional studies were analyzed separately. The five cohort studies included in this review showed and increased risk of psychosis with odds ratio: 1.47 (95% CI: 1.26–1.69), p < 0.001.Conclusions.Parental separation is a common childhood adversity associated with an increased risk of psychosis. Although the risk for an individual child of separated parents is still low, given the high proportion of couple that separate, the increased rates of psychosis may be substantial in the population. Further studies on the risk of psychosis in those with separated parents, and the explanatory factors for this association, are required.https://www.cambridge.org/core/product/identifier/S0924933819000154/type/journal_articlechildhood adversitiesdivorceparental separationpsychotic disordersschizophrenia |
| spellingShingle | Luis Ayerbe María Pérez-Piñar Quintí Foguet-Boreu Salma Ayis Psychosis in children of separated parents: A systematic review and meta-analysis European Psychiatry childhood adversities divorce parental separation psychotic disorders schizophrenia |
| title | Psychosis in children of separated parents: A systematic review and meta-analysis |
| title_full | Psychosis in children of separated parents: A systematic review and meta-analysis |
| title_fullStr | Psychosis in children of separated parents: A systematic review and meta-analysis |
| title_full_unstemmed | Psychosis in children of separated parents: A systematic review and meta-analysis |
| title_short | Psychosis in children of separated parents: A systematic review and meta-analysis |
| title_sort | psychosis in children of separated parents a systematic review and meta analysis |
| topic | childhood adversities divorce parental separation psychotic disorders schizophrenia |
| url | https://www.cambridge.org/core/product/identifier/S0924933819000154/type/journal_article |
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