Simultaneous determination of chloramphenicol and tinidazole by electrochemical analysis using MnO2/electrochemically reduced graphene oxide modified electrode
Manganese (IV) oxide/electrochemically reduced graphene oxide (MnO2/ErGO) composite was synthesized in an oxidation-reduction process followed by electrochemical reduction. The obtained materials were characterized with X-ray diffraction (XRD), electrochemical impedance spectroscopy (EIS), and scann...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-09-01
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| Series: | Journal of Science: Advanced Materials and Devices |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2468217923000618 |
| _version_ | 1827860778258006016 |
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| author | Nguyen Hai Phong Ho Xuan Anh Vu Nguyen Van Hop Nguyen Duc Vu Quyen Ho Van Minh Hai Nguyen Dinh Luyen Pham Khac Lieu Dinh Quang Khieu |
| author_facet | Nguyen Hai Phong Ho Xuan Anh Vu Nguyen Van Hop Nguyen Duc Vu Quyen Ho Van Minh Hai Nguyen Dinh Luyen Pham Khac Lieu Dinh Quang Khieu |
| author_sort | Nguyen Hai Phong |
| collection | DOAJ |
| description | Manganese (IV) oxide/electrochemically reduced graphene oxide (MnO2/ErGO) composite was synthesized in an oxidation-reduction process followed by electrochemical reduction. The obtained materials were characterized with X-ray diffraction (XRD), electrochemical impedance spectroscopy (EIS), and scanning electron microscopy (SEM) with energy-dispersive X-ray mapping (EDX mapping). The electrochemical reduction of a manganese dioxide/GO film pre-cast on a glassy carbon electrode to rGO was performed by using the chronoamperometric method for preparing the MnO2/ErGO modified electrode. The obtained modified electrode was employed to simultaneously determine chloramphenicol (CAP) and tinidazole (TNZ) with linear sweep adsorptive cathodic stripping voltammetry (LS-AdCSV). The effect of experimental parameters, e.g., potential and time of accumulation, pH of the buffered solutions, and the potential sweep rate on the response, was examined. Under the optimal conditions, the modified electrode shows a wide linear response for the concentration of CAP and TNZ in the range of 0.1–20 μM with a detection limit of 0.58 and 0.33 μM. The practicability of the developed sensor was explored by detecting CAP and TNZ individually or simultaneously in honey, eye drops, and tablet samples with satisfactory results. |
| first_indexed | 2024-03-12T13:27:45Z |
| format | Article |
| id | doaj.art-b360788cd50a48f680a9a4b7985031e7 |
| institution | Directory Open Access Journal |
| issn | 2468-2179 |
| language | English |
| last_indexed | 2024-03-12T13:27:45Z |
| publishDate | 2023-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Science: Advanced Materials and Devices |
| spelling | doaj.art-b360788cd50a48f680a9a4b7985031e72023-08-25T04:24:33ZengElsevierJournal of Science: Advanced Materials and Devices2468-21792023-09-0183100592Simultaneous determination of chloramphenicol and tinidazole by electrochemical analysis using MnO2/electrochemically reduced graphene oxide modified electrodeNguyen Hai Phong0Ho Xuan Anh Vu1Nguyen Van Hop2Nguyen Duc Vu Quyen3Ho Van Minh Hai4Nguyen Dinh Luyen5Pham Khac Lieu6Dinh Quang Khieu7University of Sciences, Hue University, 530000, Viet NamUniversity of Sciences, Hue University, 530000, Viet Nam; Corresponding author.University of Sciences, Hue University, 530000, Viet NamUniversity of Sciences, Hue University, 530000, Viet NamUniversity of Sciences, Hue University, 530000, Viet NamUniversity of Education, Hue University, 530000, Viet NamHue University, 530000, Viet NamUniversity of Sciences, Hue University, 530000, Viet Nam; Corresponding author.Manganese (IV) oxide/electrochemically reduced graphene oxide (MnO2/ErGO) composite was synthesized in an oxidation-reduction process followed by electrochemical reduction. The obtained materials were characterized with X-ray diffraction (XRD), electrochemical impedance spectroscopy (EIS), and scanning electron microscopy (SEM) with energy-dispersive X-ray mapping (EDX mapping). The electrochemical reduction of a manganese dioxide/GO film pre-cast on a glassy carbon electrode to rGO was performed by using the chronoamperometric method for preparing the MnO2/ErGO modified electrode. The obtained modified electrode was employed to simultaneously determine chloramphenicol (CAP) and tinidazole (TNZ) with linear sweep adsorptive cathodic stripping voltammetry (LS-AdCSV). The effect of experimental parameters, e.g., potential and time of accumulation, pH of the buffered solutions, and the potential sweep rate on the response, was examined. Under the optimal conditions, the modified electrode shows a wide linear response for the concentration of CAP and TNZ in the range of 0.1–20 μM with a detection limit of 0.58 and 0.33 μM. The practicability of the developed sensor was explored by detecting CAP and TNZ individually or simultaneously in honey, eye drops, and tablet samples with satisfactory results.http://www.sciencedirect.com/science/article/pii/S2468217923000618ChloramphenicolElectrochemically reduced graphene oxideManganese dioxideTinidazole |
| spellingShingle | Nguyen Hai Phong Ho Xuan Anh Vu Nguyen Van Hop Nguyen Duc Vu Quyen Ho Van Minh Hai Nguyen Dinh Luyen Pham Khac Lieu Dinh Quang Khieu Simultaneous determination of chloramphenicol and tinidazole by electrochemical analysis using MnO2/electrochemically reduced graphene oxide modified electrode Journal of Science: Advanced Materials and Devices Chloramphenicol Electrochemically reduced graphene oxide Manganese dioxide Tinidazole |
| title | Simultaneous determination of chloramphenicol and tinidazole by electrochemical analysis using MnO2/electrochemically reduced graphene oxide modified electrode |
| title_full | Simultaneous determination of chloramphenicol and tinidazole by electrochemical analysis using MnO2/electrochemically reduced graphene oxide modified electrode |
| title_fullStr | Simultaneous determination of chloramphenicol and tinidazole by electrochemical analysis using MnO2/electrochemically reduced graphene oxide modified electrode |
| title_full_unstemmed | Simultaneous determination of chloramphenicol and tinidazole by electrochemical analysis using MnO2/electrochemically reduced graphene oxide modified electrode |
| title_short | Simultaneous determination of chloramphenicol and tinidazole by electrochemical analysis using MnO2/electrochemically reduced graphene oxide modified electrode |
| title_sort | simultaneous determination of chloramphenicol and tinidazole by electrochemical analysis using mno2 electrochemically reduced graphene oxide modified electrode |
| topic | Chloramphenicol Electrochemically reduced graphene oxide Manganese dioxide Tinidazole |
| url | http://www.sciencedirect.com/science/article/pii/S2468217923000618 |
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