Micropartículas nanorrevestidas contendo um fármaco modelo hidrofóbico: preparação em etapa única e caracterização biofarmacêutica Nanocapsule-coated microparticles prepared in one step: characterization and in vitro drug release profiles evaluation

Micropartículas nanorrevestidas contendo um fármaco modelo hidrofóbico: preparação em etapa única e caracterização biofarmacêutica Nanocapsule-coated microparticles prepared in one step: characterization and in vitro drug release profiles evaluation

<abstract language="eng">The aim of this work was to prepare and characterize spray-dried nanocapsule-coated microparticles obtained in one step, using indomethacin as a hydrophobic drug model and poly(e-caprolactone) or Eudragit® RS100, as polymers. Nanocapsule-coated microparticles...

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Bibliographic Details
Main Authors: Gislane Scholze Domingues, Sílvia Stanisçuaski Guterres, Ruy Carlos Ruver Beck, Adriana Raffin Pohlmann
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2008-01-01
Series:Química Nova
Subjects:
indomethacin
microparticles
nanocapsules
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000800009

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