Describing financial toxicity among cancer patients in different income countries: a systematic review and meta-analysis
BackgroundThere is limited evidence of financial toxicity (FT) among cancer patients from countries of various income levels. Hence, this study aimed to determine the prevalence of objective and subjective FT and their measurements in relation to cancer treatment.MethodsPubMed, Science Direct, Scopu...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2024-01-01
|
| Series: | Frontiers in Public Health |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2023.1266533/full |
| _version_ | 1827393858680389632 |
|---|---|
| author | Meram Azzani Meram Azzani Wahib Mohammed Atroosh Wahib Mohammed Atroosh Deepa Anbazhagan Vinoth Kumarasamy Mona Mohamed Ibrahim Abdalla |
| author_facet | Meram Azzani Meram Azzani Wahib Mohammed Atroosh Wahib Mohammed Atroosh Deepa Anbazhagan Vinoth Kumarasamy Mona Mohamed Ibrahim Abdalla |
| author_sort | Meram Azzani |
| collection | DOAJ |
| description | BackgroundThere is limited evidence of financial toxicity (FT) among cancer patients from countries of various income levels. Hence, this study aimed to determine the prevalence of objective and subjective FT and their measurements in relation to cancer treatment.MethodsPubMed, Science Direct, Scopus, and CINAHL databases were searched to find studies that examined FT. There was no limit on the design or setting of the study. Random-effects meta-analysis was utilized to obtain the pooled prevalence of objective FT.ResultsOut of 244 identified studies during the initial screening, only 64 studies were included in this review. The catastrophic health expenditure (CHE) method was often used in the included studies to determine the objective FT. The pooled prevalence of CHE was 47% (95% CI: 24.0–70.0) in middle- and high-income countries, and the highest percentage was noted in low-income countries (74.4%). A total of 30 studies focused on subjective FT, of which 9 used the Comprehensive Score for FT (COST) tool and reported median scores ranging between 17.0 and 31.9.ConclusionThis study shows that cancer patients from various income-group countries experienced a significant financial burden during their treatment. It is imperative to conduct further studies on interventions and policies that can lower FT caused by cancer treatment. |
| first_indexed | 2024-03-08T17:57:33Z |
| format | Article |
| id | doaj.art-b363392db3f5455a93d61847b358695c |
| institution | Directory Open Access Journal |
| issn | 2296-2565 |
| language | English |
| last_indexed | 2024-03-08T17:57:33Z |
| publishDate | 2024-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj.art-b363392db3f5455a93d61847b358695c2024-01-02T04:11:38ZengFrontiers Media S.A.Frontiers in Public Health2296-25652024-01-011110.3389/fpubh.2023.12665331266533Describing financial toxicity among cancer patients in different income countries: a systematic review and meta-analysisMeram Azzani0Meram Azzani1Wahib Mohammed Atroosh2Wahib Mohammed Atroosh3Deepa Anbazhagan4Vinoth Kumarasamy5Mona Mohamed Ibrahim Abdalla6Department of Public Health Medicine, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh, Selangor, MalaysiaCentre of Occupational Safety, Health and Wellbeing, Universiti Teknologi MARA, Puncak Alam, Selangor, MalaysiaDepartment of Parasitology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, MalaysiaDepartment of Microbiology and Parasitology, Faculty of Medicine and Health Sciences, University of Aden, Aden, YemenDepartment of Microbiology, International Medical School (IMS), Management & Science University (MSU), Shah Alam, Selangor, MalaysiaDepartment of Parasitology and Medical Entomology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Kuala Lumpur, MalaysiaPhysiology Department, Human Biology Division, School of Medicine, International Medical University (IMU), Kuala Lumpur, MalaysiaBackgroundThere is limited evidence of financial toxicity (FT) among cancer patients from countries of various income levels. Hence, this study aimed to determine the prevalence of objective and subjective FT and their measurements in relation to cancer treatment.MethodsPubMed, Science Direct, Scopus, and CINAHL databases were searched to find studies that examined FT. There was no limit on the design or setting of the study. Random-effects meta-analysis was utilized to obtain the pooled prevalence of objective FT.ResultsOut of 244 identified studies during the initial screening, only 64 studies were included in this review. The catastrophic health expenditure (CHE) method was often used in the included studies to determine the objective FT. The pooled prevalence of CHE was 47% (95% CI: 24.0–70.0) in middle- and high-income countries, and the highest percentage was noted in low-income countries (74.4%). A total of 30 studies focused on subjective FT, of which 9 used the Comprehensive Score for FT (COST) tool and reported median scores ranging between 17.0 and 31.9.ConclusionThis study shows that cancer patients from various income-group countries experienced a significant financial burden during their treatment. It is imperative to conduct further studies on interventions and policies that can lower FT caused by cancer treatment.https://www.frontiersin.org/articles/10.3389/fpubh.2023.1266533/fulldirect medical costdirect non-medical costindirect medical costcatastrophic health expenditureperceived financial hardshipsystematic review |
| spellingShingle | Meram Azzani Meram Azzani Wahib Mohammed Atroosh Wahib Mohammed Atroosh Deepa Anbazhagan Vinoth Kumarasamy Mona Mohamed Ibrahim Abdalla Describing financial toxicity among cancer patients in different income countries: a systematic review and meta-analysis Frontiers in Public Health direct medical cost direct non-medical cost indirect medical cost catastrophic health expenditure perceived financial hardship systematic review |
| title | Describing financial toxicity among cancer patients in different income countries: a systematic review and meta-analysis |
| title_full | Describing financial toxicity among cancer patients in different income countries: a systematic review and meta-analysis |
| title_fullStr | Describing financial toxicity among cancer patients in different income countries: a systematic review and meta-analysis |
| title_full_unstemmed | Describing financial toxicity among cancer patients in different income countries: a systematic review and meta-analysis |
| title_short | Describing financial toxicity among cancer patients in different income countries: a systematic review and meta-analysis |
| title_sort | describing financial toxicity among cancer patients in different income countries a systematic review and meta analysis |
| topic | direct medical cost direct non-medical cost indirect medical cost catastrophic health expenditure perceived financial hardship systematic review |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2023.1266533/full |
| work_keys_str_mv | AT meramazzani describingfinancialtoxicityamongcancerpatientsindifferentincomecountriesasystematicreviewandmetaanalysis AT meramazzani describingfinancialtoxicityamongcancerpatientsindifferentincomecountriesasystematicreviewandmetaanalysis AT wahibmohammedatroosh describingfinancialtoxicityamongcancerpatientsindifferentincomecountriesasystematicreviewandmetaanalysis AT wahibmohammedatroosh describingfinancialtoxicityamongcancerpatientsindifferentincomecountriesasystematicreviewandmetaanalysis AT deepaanbazhagan describingfinancialtoxicityamongcancerpatientsindifferentincomecountriesasystematicreviewandmetaanalysis AT vinothkumarasamy describingfinancialtoxicityamongcancerpatientsindifferentincomecountriesasystematicreviewandmetaanalysis AT monamohamedibrahimabdalla describingfinancialtoxicityamongcancerpatientsindifferentincomecountriesasystematicreviewandmetaanalysis |