Prevalence of Right Ventricular Dysfunction & Pulmonary Hypertension and their Relationship to the Number of Hemodialysis Sessions in Patients of End-Stage Renal Disease (ESRD)
Introduction: Chronic hemodialysis (HD) ends up with right ventricular (RV) dysfunction and increased pulmonary hypertension (PHTN). Left to right shunt in dialysis patients due to arterio-venous fistula (AVF) causes chronic volume overload, independent of rise in body water leading to worsening RV...
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| Format: | Article |
| Language: | English |
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Shaikh Zayed Medical Complex, Lahore
2021-06-01
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| Series: | Proceedings |
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| Online Access: | https://proceedings-szmc.org.pk/index.php/szmc/article/view/143 |
| _version_ | 1817985941025849344 |
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| author | Rakesh Bahadur Adhikari Qazi Abdul Saboor Mateen Akram Saira Fayyaz Husnain Bashir Muhammad Rizwan-ul-Haque |
| author_facet | Rakesh Bahadur Adhikari Qazi Abdul Saboor Mateen Akram Saira Fayyaz Husnain Bashir Muhammad Rizwan-ul-Haque |
| author_sort | Rakesh Bahadur Adhikari |
| collection | DOAJ |
| description | Introduction: Chronic hemodialysis (HD) ends up with right ventricular (RV) dysfunction and increased pulmonary hypertension (PHTN). Left to right shunt in dialysis patients due to arterio-venous fistula (AVF) causes chronic volume overload, independent of rise in body water leading to worsening RV overload and RV dysfunction (RVD).
Aims & Objectives: To determine the prevalence of RV dysfunction & pulmonary hypertension and its relationship to the number of dialysis sessions in patients of ESRD.
Place and duration of study: Department of Cardiology & Nephrology, Sheikh Zayed Hospital, Lahore for one year from March 2016 - March 2017.
Material & Methods: This cross-sectional analytical hospital based study enrolled 145 Patients of End-Stage Renal Disease (ESRD) on regular 4-hours HD sessions at two or more times per week for at least 3 months. Echocardiography
(Echo) with 2-D, M (Motion) Mode & Doppler studies were done. RV dysfunction by TAPSE value less than 15mm & PHTN by Systolic pulmonary artery pressure >35 mm Hg or tricuspid regurgitation velocity (VTR) ?2m/s at rest were noted. Data was analyzed on SPSS version 20.
Results: RV dysfunction was seen in 40.7% (59) of patients and the frequency rose across the 4 dialysis session groups (13.8%, 37.3%, 51.7% & 100%, p<0.001). PHTN was observed in 44.1% of the patients and the prevalence progressively increased across the groups (17.2%, 45.1%, 53.3% & 80.01%, p<0.003). There was significant association between RVD and PHTN (p=0.011).
Conclusion: We observed positive correlation between RV dysfunction and PHTN with total number of hemodialysis sessions. Early detection of sub-clinical RV dysfunction may improve mortality and morbidity by optimizing treatment options. |
| first_indexed | 2024-04-14T00:04:11Z |
| format | Article |
| id | doaj.art-b364c46e8c3f46c2af34f384560002b6 |
| institution | Directory Open Access Journal |
| issn | 1815-4905 2518-203X |
| language | English |
| last_indexed | 2024-04-14T00:04:11Z |
| publishDate | 2021-06-01 |
| publisher | Shaikh Zayed Medical Complex, Lahore |
| record_format | Article |
| series | Proceedings |
| spelling | doaj.art-b364c46e8c3f46c2af34f384560002b62022-12-22T02:23:36ZengShaikh Zayed Medical Complex, LahoreProceedings1815-49052518-203X2021-06-01353646810.47489/PSZMC-811-35-3-64-68143Prevalence of Right Ventricular Dysfunction & Pulmonary Hypertension and their Relationship to the Number of Hemodialysis Sessions in Patients of End-Stage Renal Disease (ESRD)Rakesh Bahadur Adhikari0Qazi Abdul Saboor1Mateen Akram2Saira Fayyaz3Husnain Bashir4Muhammad Rizwan-ul-Haque5Department of Cardiology, Shahid Gangalal National Heart Centre, Kathmandu, NepalDepartment of Cardiology, Shaikh Zayed Medical Complex, LahoreDepartment of Nephrology, Shaikh Zayed Medical Complex, LahoreDepartment of Cardiology, City Care Hospital, Khanewal Department of Cardiology, Shaikh Zayed Medical Complex, LahoreDepartment of Nephrology, Shaikh Zayed Medical Complex, LahoreIntroduction: Chronic hemodialysis (HD) ends up with right ventricular (RV) dysfunction and increased pulmonary hypertension (PHTN). Left to right shunt in dialysis patients due to arterio-venous fistula (AVF) causes chronic volume overload, independent of rise in body water leading to worsening RV overload and RV dysfunction (RVD). Aims & Objectives: To determine the prevalence of RV dysfunction & pulmonary hypertension and its relationship to the number of dialysis sessions in patients of ESRD. Place and duration of study: Department of Cardiology & Nephrology, Sheikh Zayed Hospital, Lahore for one year from March 2016 - March 2017. Material & Methods: This cross-sectional analytical hospital based study enrolled 145 Patients of End-Stage Renal Disease (ESRD) on regular 4-hours HD sessions at two or more times per week for at least 3 months. Echocardiography (Echo) with 2-D, M (Motion) Mode & Doppler studies were done. RV dysfunction by TAPSE value less than 15mm & PHTN by Systolic pulmonary artery pressure >35 mm Hg or tricuspid regurgitation velocity (VTR) ?2m/s at rest were noted. Data was analyzed on SPSS version 20. Results: RV dysfunction was seen in 40.7% (59) of patients and the frequency rose across the 4 dialysis session groups (13.8%, 37.3%, 51.7% & 100%, p<0.001). PHTN was observed in 44.1% of the patients and the prevalence progressively increased across the groups (17.2%, 45.1%, 53.3% & 80.01%, p<0.003). There was significant association between RVD and PHTN (p=0.011). Conclusion: We observed positive correlation between RV dysfunction and PHTN with total number of hemodialysis sessions. Early detection of sub-clinical RV dysfunction may improve mortality and morbidity by optimizing treatment options.https://proceedings-szmc.org.pk/index.php/szmc/article/view/143esrd patients on hd, echo, rv dysfunction, phtn. |
| spellingShingle | Rakesh Bahadur Adhikari Qazi Abdul Saboor Mateen Akram Saira Fayyaz Husnain Bashir Muhammad Rizwan-ul-Haque Prevalence of Right Ventricular Dysfunction & Pulmonary Hypertension and their Relationship to the Number of Hemodialysis Sessions in Patients of End-Stage Renal Disease (ESRD) Proceedings esrd patients on hd, echo, rv dysfunction, phtn. |
| title | Prevalence of Right Ventricular Dysfunction & Pulmonary Hypertension and their Relationship to the Number of Hemodialysis Sessions in Patients of End-Stage Renal Disease (ESRD) |
| title_full | Prevalence of Right Ventricular Dysfunction & Pulmonary Hypertension and their Relationship to the Number of Hemodialysis Sessions in Patients of End-Stage Renal Disease (ESRD) |
| title_fullStr | Prevalence of Right Ventricular Dysfunction & Pulmonary Hypertension and their Relationship to the Number of Hemodialysis Sessions in Patients of End-Stage Renal Disease (ESRD) |
| title_full_unstemmed | Prevalence of Right Ventricular Dysfunction & Pulmonary Hypertension and their Relationship to the Number of Hemodialysis Sessions in Patients of End-Stage Renal Disease (ESRD) |
| title_short | Prevalence of Right Ventricular Dysfunction & Pulmonary Hypertension and their Relationship to the Number of Hemodialysis Sessions in Patients of End-Stage Renal Disease (ESRD) |
| title_sort | prevalence of right ventricular dysfunction pulmonary hypertension and their relationship to the number of hemodialysis sessions in patients of end stage renal disease esrd |
| topic | esrd patients on hd, echo, rv dysfunction, phtn. |
| url | https://proceedings-szmc.org.pk/index.php/szmc/article/view/143 |
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