Long-Term Use of Metformin Is Associated With Reduced Risk of Cognitive Impairment With Alleviation of Cerebral Small Vessel Disease Burden in Patients With Type 2 Diabetes

Long-Term Use of Metformin Is Associated With Reduced Risk of Cognitive Impairment With Alleviation of Cerebral Small Vessel Disease Burden in Patients With Type 2 Diabetes

Objective: Type 2 diabetes (T2D) is a risk factor for cognitive impairment and cerebral small vessel disease (CSVD). The relation of metformin use and cognitive impairment or CSVD is not clear. The objective of this study was to investigate the cross-sectional effects of long-term use of metformin o...

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Bibliographic Details
Main Authors: Zhenjie Teng, Jing Feng, Qianqian Qi, Yanhong Dong, Yining Xiao, Xiaohua Xie, Nan Meng, Huifang Chen, Wenhui Zhang, Peiyuan Lv
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Aging Neuroscience
Subjects:
metformin
cerebral small vessel disease
cognitive impairment
diabetes
relationship
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.773797/full

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