Systematic review of interventions aimed at improving HIV adherence to care in low- and middle-income countries in Sub-Saharan Africa

Long-term adherence to antiretroviral medication continues to present as a challenge along the continuum of the HIV care cascade. HIV interventions and support programs are significantly threatened in resource-limited settings by challenges in maintaining long-term follow-up for ART adherence. We so...

Full description

Bibliographic Details
Main Authors: Laura E. Pugh, Jacob S. Roberts, Nikita Viswasam, Elizabeth Hahn, Sophia Ryan, Ghilane Turpin, Carrie E. Lyons, Stefan Baral, Bhakti Hansoti
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Journal of Infection and Public Health
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1876034122002180
_version_ 1798000273997692928
author Laura E. Pugh
Jacob S. Roberts
Nikita Viswasam
Elizabeth Hahn
Sophia Ryan
Ghilane Turpin
Carrie E. Lyons
Stefan Baral
Bhakti Hansoti
author_facet Laura E. Pugh
Jacob S. Roberts
Nikita Viswasam
Elizabeth Hahn
Sophia Ryan
Ghilane Turpin
Carrie E. Lyons
Stefan Baral
Bhakti Hansoti
author_sort Laura E. Pugh
collection DOAJ
description Long-term adherence to antiretroviral medication continues to present as a challenge along the continuum of the HIV care cascade. HIV interventions and support programs are significantly threatened in resource-limited settings by challenges in maintaining long-term follow-up for ART adherence. We sought to complete a systematic review to comprehensively examine ART adherence and retention in care interventions in Sub-Saharan Africa and to report on the implementation of interventions in real-world settings to inform future health investments in HIV care. Interventions were grouped according to their impact on individual, community, and health-systems levels. While a vast majority of studies evaluated a combination of interventions, those studies that incorporated the community as a resource were most successful. In addition, providing education and behavior reminders proved effective and should be accompanied by community and peer efforts for best results. Multi-level interventions, such as combining individual and community-level interventions showed promising results for long term ART adherence.
first_indexed 2024-04-11T11:17:06Z
format Article
id doaj.art-b36a25e9499b46b697af02a0379e2ccb
institution Directory Open Access Journal
issn 1876-0341
language English
last_indexed 2024-04-11T11:17:06Z
publishDate 2022-10-01
publisher Elsevier
record_format Article
series Journal of Infection and Public Health
spelling doaj.art-b36a25e9499b46b697af02a0379e2ccb2022-12-22T04:27:11ZengElsevierJournal of Infection and Public Health1876-03412022-10-01151010531060Systematic review of interventions aimed at improving HIV adherence to care in low- and middle-income countries in Sub-Saharan AfricaLaura E. Pugh0Jacob S. Roberts1Nikita Viswasam2Elizabeth Hahn3Sophia Ryan4Ghilane Turpin5Carrie E. Lyons6Stefan Baral7Bhakti Hansoti8School of Medicine, Johns Hopkins University, Baltimore, Maryland, USASchool of Medicine, Johns Hopkins University, Baltimore, Maryland, USACenter for Public Health and Human Rights, Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USACenter for Public Health and Human Rights, Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USACenter for Public Health and Human Rights, Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USACenter for Public Health and Human Rights, Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USACenter for Public Health and Human Rights, Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USACenter for Public Health and Human Rights, Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USADepartment of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Department of International Health, Bloomberg School of Public Health, Baltimore, Maryland, USA; Correspondence to: Department of Emergency, Medicine Suite 200, 5801 Smith Avenue, Baltimore, Maryland 21209, USA.Long-term adherence to antiretroviral medication continues to present as a challenge along the continuum of the HIV care cascade. HIV interventions and support programs are significantly threatened in resource-limited settings by challenges in maintaining long-term follow-up for ART adherence. We sought to complete a systematic review to comprehensively examine ART adherence and retention in care interventions in Sub-Saharan Africa and to report on the implementation of interventions in real-world settings to inform future health investments in HIV care. Interventions were grouped according to their impact on individual, community, and health-systems levels. While a vast majority of studies evaluated a combination of interventions, those studies that incorporated the community as a resource were most successful. In addition, providing education and behavior reminders proved effective and should be accompanied by community and peer efforts for best results. Multi-level interventions, such as combining individual and community-level interventions showed promising results for long term ART adherence.http://www.sciencedirect.com/science/article/pii/S1876034122002180Human immunodeficiency virus (HIV)AdherenceSystematic analysisSub-Saharan Africa
spellingShingle Laura E. Pugh
Jacob S. Roberts
Nikita Viswasam
Elizabeth Hahn
Sophia Ryan
Ghilane Turpin
Carrie E. Lyons
Stefan Baral
Bhakti Hansoti
Systematic review of interventions aimed at improving HIV adherence to care in low- and middle-income countries in Sub-Saharan Africa
Journal of Infection and Public Health
Human immunodeficiency virus (HIV)
Adherence
Systematic analysis
Sub-Saharan Africa
title Systematic review of interventions aimed at improving HIV adherence to care in low- and middle-income countries in Sub-Saharan Africa
title_full Systematic review of interventions aimed at improving HIV adherence to care in low- and middle-income countries in Sub-Saharan Africa
title_fullStr Systematic review of interventions aimed at improving HIV adherence to care in low- and middle-income countries in Sub-Saharan Africa
title_full_unstemmed Systematic review of interventions aimed at improving HIV adherence to care in low- and middle-income countries in Sub-Saharan Africa
title_short Systematic review of interventions aimed at improving HIV adherence to care in low- and middle-income countries in Sub-Saharan Africa
title_sort systematic review of interventions aimed at improving hiv adherence to care in low and middle income countries in sub saharan africa
topic Human immunodeficiency virus (HIV)
Adherence
Systematic analysis
Sub-Saharan Africa
url http://www.sciencedirect.com/science/article/pii/S1876034122002180
work_keys_str_mv AT lauraepugh systematicreviewofinterventionsaimedatimprovinghivadherencetocareinlowandmiddleincomecountriesinsubsaharanafrica
AT jacobsroberts systematicreviewofinterventionsaimedatimprovinghivadherencetocareinlowandmiddleincomecountriesinsubsaharanafrica
AT nikitaviswasam systematicreviewofinterventionsaimedatimprovinghivadherencetocareinlowandmiddleincomecountriesinsubsaharanafrica
AT elizabethhahn systematicreviewofinterventionsaimedatimprovinghivadherencetocareinlowandmiddleincomecountriesinsubsaharanafrica
AT sophiaryan systematicreviewofinterventionsaimedatimprovinghivadherencetocareinlowandmiddleincomecountriesinsubsaharanafrica
AT ghilaneturpin systematicreviewofinterventionsaimedatimprovinghivadherencetocareinlowandmiddleincomecountriesinsubsaharanafrica
AT carrieelyons systematicreviewofinterventionsaimedatimprovinghivadherencetocareinlowandmiddleincomecountriesinsubsaharanafrica
AT stefanbaral systematicreviewofinterventionsaimedatimprovinghivadherencetocareinlowandmiddleincomecountriesinsubsaharanafrica
AT bhaktihansoti systematicreviewofinterventionsaimedatimprovinghivadherencetocareinlowandmiddleincomecountriesinsubsaharanafrica