Systematic review of interventions aimed at improving HIV adherence to care in low- and middle-income countries in Sub-Saharan Africa
Long-term adherence to antiretroviral medication continues to present as a challenge along the continuum of the HIV care cascade. HIV interventions and support programs are significantly threatened in resource-limited settings by challenges in maintaining long-term follow-up for ART adherence. We so...
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Format: | Article |
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Elsevier
2022-10-01
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Series: | Journal of Infection and Public Health |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S1876034122002180 |
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author | Laura E. Pugh Jacob S. Roberts Nikita Viswasam Elizabeth Hahn Sophia Ryan Ghilane Turpin Carrie E. Lyons Stefan Baral Bhakti Hansoti |
author_facet | Laura E. Pugh Jacob S. Roberts Nikita Viswasam Elizabeth Hahn Sophia Ryan Ghilane Turpin Carrie E. Lyons Stefan Baral Bhakti Hansoti |
author_sort | Laura E. Pugh |
collection | DOAJ |
description | Long-term adherence to antiretroviral medication continues to present as a challenge along the continuum of the HIV care cascade. HIV interventions and support programs are significantly threatened in resource-limited settings by challenges in maintaining long-term follow-up for ART adherence. We sought to complete a systematic review to comprehensively examine ART adherence and retention in care interventions in Sub-Saharan Africa and to report on the implementation of interventions in real-world settings to inform future health investments in HIV care. Interventions were grouped according to their impact on individual, community, and health-systems levels. While a vast majority of studies evaluated a combination of interventions, those studies that incorporated the community as a resource were most successful. In addition, providing education and behavior reminders proved effective and should be accompanied by community and peer efforts for best results. Multi-level interventions, such as combining individual and community-level interventions showed promising results for long term ART adherence. |
first_indexed | 2024-04-11T11:17:06Z |
format | Article |
id | doaj.art-b36a25e9499b46b697af02a0379e2ccb |
institution | Directory Open Access Journal |
issn | 1876-0341 |
language | English |
last_indexed | 2024-04-11T11:17:06Z |
publishDate | 2022-10-01 |
publisher | Elsevier |
record_format | Article |
series | Journal of Infection and Public Health |
spelling | doaj.art-b36a25e9499b46b697af02a0379e2ccb2022-12-22T04:27:11ZengElsevierJournal of Infection and Public Health1876-03412022-10-01151010531060Systematic review of interventions aimed at improving HIV adherence to care in low- and middle-income countries in Sub-Saharan AfricaLaura E. Pugh0Jacob S. Roberts1Nikita Viswasam2Elizabeth Hahn3Sophia Ryan4Ghilane Turpin5Carrie E. Lyons6Stefan Baral7Bhakti Hansoti8School of Medicine, Johns Hopkins University, Baltimore, Maryland, USASchool of Medicine, Johns Hopkins University, Baltimore, Maryland, USACenter for Public Health and Human Rights, Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USACenter for Public Health and Human Rights, Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USACenter for Public Health and Human Rights, Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USACenter for Public Health and Human Rights, Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USACenter for Public Health and Human Rights, Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USACenter for Public Health and Human Rights, Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USADepartment of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Department of International Health, Bloomberg School of Public Health, Baltimore, Maryland, USA; Correspondence to: Department of Emergency, Medicine Suite 200, 5801 Smith Avenue, Baltimore, Maryland 21209, USA.Long-term adherence to antiretroviral medication continues to present as a challenge along the continuum of the HIV care cascade. HIV interventions and support programs are significantly threatened in resource-limited settings by challenges in maintaining long-term follow-up for ART adherence. We sought to complete a systematic review to comprehensively examine ART adherence and retention in care interventions in Sub-Saharan Africa and to report on the implementation of interventions in real-world settings to inform future health investments in HIV care. Interventions were grouped according to their impact on individual, community, and health-systems levels. While a vast majority of studies evaluated a combination of interventions, those studies that incorporated the community as a resource were most successful. In addition, providing education and behavior reminders proved effective and should be accompanied by community and peer efforts for best results. Multi-level interventions, such as combining individual and community-level interventions showed promising results for long term ART adherence.http://www.sciencedirect.com/science/article/pii/S1876034122002180Human immunodeficiency virus (HIV)AdherenceSystematic analysisSub-Saharan Africa |
spellingShingle | Laura E. Pugh Jacob S. Roberts Nikita Viswasam Elizabeth Hahn Sophia Ryan Ghilane Turpin Carrie E. Lyons Stefan Baral Bhakti Hansoti Systematic review of interventions aimed at improving HIV adherence to care in low- and middle-income countries in Sub-Saharan Africa Journal of Infection and Public Health Human immunodeficiency virus (HIV) Adherence Systematic analysis Sub-Saharan Africa |
title | Systematic review of interventions aimed at improving HIV adherence to care in low- and middle-income countries in Sub-Saharan Africa |
title_full | Systematic review of interventions aimed at improving HIV adherence to care in low- and middle-income countries in Sub-Saharan Africa |
title_fullStr | Systematic review of interventions aimed at improving HIV adherence to care in low- and middle-income countries in Sub-Saharan Africa |
title_full_unstemmed | Systematic review of interventions aimed at improving HIV adherence to care in low- and middle-income countries in Sub-Saharan Africa |
title_short | Systematic review of interventions aimed at improving HIV adherence to care in low- and middle-income countries in Sub-Saharan Africa |
title_sort | systematic review of interventions aimed at improving hiv adherence to care in low and middle income countries in sub saharan africa |
topic | Human immunodeficiency virus (HIV) Adherence Systematic analysis Sub-Saharan Africa |
url | http://www.sciencedirect.com/science/article/pii/S1876034122002180 |
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