Abdominal Tuberculosis Mimicking Ovarian Cancer: A Case Report and Review of the Literature

Ikhwan Rinaldi,1,2 Abdul Muthalib,1,2 Djaja Gosal,2 Teguh Wijayadi,2 Barlian Sutedja,3 Tjondro Setiawan,4 Andika Gunawan,5 Nelly Susanto,4 Lingga Magdalena,4 Diah Rini Handjari,6,7 Fetisari Kurniawan,6,7 Aisyah Rifani,8 Kevin Winston8 1Divison of Hematology and Medical Oncology, Department of Intern...

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Main Authors: Rinaldi I, Muthalib A, Gosal D, Wijayadi T, Sutedja B, Setiawan T, Gunawan A, Susanto N, Magdalena L, Handjari DR, Kurniawan F, Rifani A, Winston K
Format: Article
Language:English
Published: Dove Medical Press 2022-04-01
Series:International Medical Case Reports Journal
Subjects:
Online Access:https://www.dovepress.com/abdominal-tuberculosis-mimicking-ovarian-cancer-a-case-report-and-revi-peer-reviewed-fulltext-article-IMCRJ
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author Rinaldi I
Muthalib A
Gosal D
Wijayadi T
Sutedja B
Setiawan T
Gunawan A
Susanto N
Magdalena L
Handjari DR
Kurniawan F
Rifani A
Winston K
author_facet Rinaldi I
Muthalib A
Gosal D
Wijayadi T
Sutedja B
Setiawan T
Gunawan A
Susanto N
Magdalena L
Handjari DR
Kurniawan F
Rifani A
Winston K
author_sort Rinaldi I
collection DOAJ
description Ikhwan Rinaldi,1,2 Abdul Muthalib,1,2 Djaja Gosal,2 Teguh Wijayadi,2 Barlian Sutedja,3 Tjondro Setiawan,4 Andika Gunawan,5 Nelly Susanto,4 Lingga Magdalena,4 Diah Rini Handjari,6,7 Fetisari Kurniawan,6,7 Aisyah Rifani,8 Kevin Winston8 1Divison of Hematology and Medical Oncology, Department of Internal Medicine, Cipto Mangunkusumo National General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; 2Department of Internal Medicine, Gading Pluit Hospital, Jakarta, Indonesia; 3Departement of General Surgery, Gading Pluit Hospital, Jakarta, Indonesia; 4Departement of Radiology, Gading Pluit Hospital, Jakarta, Indonesia; 5Departement of Nuclear Medicine, Gading Pluit Hospital, Jakarta, Indonesia; 6Department of Anatomical Pathology, Cipto Mangunkusumo National General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; 7Departement of Pathology, Gading Pluit Hospital, Jakarta, Indonesia; 8Departement of Internal Medicine, Cipto Mangunkusumo National General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, IndonesiaCorrespondence: Ikhwan Rinaldi, Division of Hematology and Medical Oncology, Department of Internal Medicine, Cipto Mangunkusumo National General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Tel +62 811-177-997, Email ikhwanrinaldi@gmail.comIntroduction: Tuberculosis (TB) is a disease with high morbidity and mortality resulting from infection by Mycobacterium tuberculosis. TB can disseminate to any organ system of the body resulting in extrapulmonary tuberculosis. Interestingly, CA-125, which is a biomarker for some cancer, also rises in benign diseases such as pulmonary and extrapulmonary tuberculosis which may complicate diagnosis. In this case report, we present an abdominal tuberculosis patient that was initially presented as ovarian cancer.Case Report: A 30-year-old woman admitted to the emergency department with chief complaint of fatigue and shortness of breath since 3 months ago. She had lost around 20 kg weight in the past 5 months. She was previously suspected with ovarian cancer because of the characteristic features of malignancy, high levels of CA-125, and positive PET scan. She was later diagnosed with abdominal TB. Subsequently, the patient was given anti-TB drugs, and the patient showed clinical improvement.Conclusion: In the case of an elevated CA-125, clinicians should consider extrapulmonary TB as a differential diagnosis of ovarian cancer, especially in countries with high burden of tuberculosis.Keywords: extrapulmonary tuberculosis, CA-125, ovarian cancer, malignancy, case report
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spelling doaj.art-b36afc670ec1487bbd2ce0e1dd690d402022-12-22T03:14:11ZengDove Medical PressInternational Medical Case Reports Journal1179-142X2022-04-01Volume 1516918574400Abdominal Tuberculosis Mimicking Ovarian Cancer: A Case Report and Review of the LiteratureRinaldi IMuthalib AGosal DWijayadi TSutedja BSetiawan TGunawan ASusanto NMagdalena LHandjari DRKurniawan FRifani AWinston KIkhwan Rinaldi,1,2 Abdul Muthalib,1,2 Djaja Gosal,2 Teguh Wijayadi,2 Barlian Sutedja,3 Tjondro Setiawan,4 Andika Gunawan,5 Nelly Susanto,4 Lingga Magdalena,4 Diah Rini Handjari,6,7 Fetisari Kurniawan,6,7 Aisyah Rifani,8 Kevin Winston8 1Divison of Hematology and Medical Oncology, Department of Internal Medicine, Cipto Mangunkusumo National General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; 2Department of Internal Medicine, Gading Pluit Hospital, Jakarta, Indonesia; 3Departement of General Surgery, Gading Pluit Hospital, Jakarta, Indonesia; 4Departement of Radiology, Gading Pluit Hospital, Jakarta, Indonesia; 5Departement of Nuclear Medicine, Gading Pluit Hospital, Jakarta, Indonesia; 6Department of Anatomical Pathology, Cipto Mangunkusumo National General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; 7Departement of Pathology, Gading Pluit Hospital, Jakarta, Indonesia; 8Departement of Internal Medicine, Cipto Mangunkusumo National General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, IndonesiaCorrespondence: Ikhwan Rinaldi, Division of Hematology and Medical Oncology, Department of Internal Medicine, Cipto Mangunkusumo National General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Tel +62 811-177-997, Email ikhwanrinaldi@gmail.comIntroduction: Tuberculosis (TB) is a disease with high morbidity and mortality resulting from infection by Mycobacterium tuberculosis. TB can disseminate to any organ system of the body resulting in extrapulmonary tuberculosis. Interestingly, CA-125, which is a biomarker for some cancer, also rises in benign diseases such as pulmonary and extrapulmonary tuberculosis which may complicate diagnosis. In this case report, we present an abdominal tuberculosis patient that was initially presented as ovarian cancer.Case Report: A 30-year-old woman admitted to the emergency department with chief complaint of fatigue and shortness of breath since 3 months ago. She had lost around 20 kg weight in the past 5 months. She was previously suspected with ovarian cancer because of the characteristic features of malignancy, high levels of CA-125, and positive PET scan. She was later diagnosed with abdominal TB. Subsequently, the patient was given anti-TB drugs, and the patient showed clinical improvement.Conclusion: In the case of an elevated CA-125, clinicians should consider extrapulmonary TB as a differential diagnosis of ovarian cancer, especially in countries with high burden of tuberculosis.Keywords: extrapulmonary tuberculosis, CA-125, ovarian cancer, malignancy, case reporthttps://www.dovepress.com/abdominal-tuberculosis-mimicking-ovarian-cancer-a-case-report-and-revi-peer-reviewed-fulltext-article-IMCRJextrapulmonary tuberculosisca-125ovarian cancermalignancycase report
spellingShingle Rinaldi I
Muthalib A
Gosal D
Wijayadi T
Sutedja B
Setiawan T
Gunawan A
Susanto N
Magdalena L
Handjari DR
Kurniawan F
Rifani A
Winston K
Abdominal Tuberculosis Mimicking Ovarian Cancer: A Case Report and Review of the Literature
International Medical Case Reports Journal
extrapulmonary tuberculosis
ca-125
ovarian cancer
malignancy
case report
title Abdominal Tuberculosis Mimicking Ovarian Cancer: A Case Report and Review of the Literature
title_full Abdominal Tuberculosis Mimicking Ovarian Cancer: A Case Report and Review of the Literature
title_fullStr Abdominal Tuberculosis Mimicking Ovarian Cancer: A Case Report and Review of the Literature
title_full_unstemmed Abdominal Tuberculosis Mimicking Ovarian Cancer: A Case Report and Review of the Literature
title_short Abdominal Tuberculosis Mimicking Ovarian Cancer: A Case Report and Review of the Literature
title_sort abdominal tuberculosis mimicking ovarian cancer a case report and review of the literature
topic extrapulmonary tuberculosis
ca-125
ovarian cancer
malignancy
case report
url https://www.dovepress.com/abdominal-tuberculosis-mimicking-ovarian-cancer-a-case-report-and-revi-peer-reviewed-fulltext-article-IMCRJ
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