Germacranolide-type sesquiterpene lactones from Smallanthus sonchifolius with promising activity against Leishmania mexicana and Trypanosoma cruzi

Germacranolide-type sesquiterpene lactones from Smallanthus sonchifolius with promising activity against Leishmania mexicana and Trypanosoma cruzi

Abstract Background Leishmaniasis and Chagas disease are life-threatening illnesses caused by the protozoan parasites Leishmania spp. and Trypanosoma cruzi, respectively. They are known as “neglected diseases” due to the lack of effective drug treatments and the scarcity of research work devoted to...

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Bibliographic Details
Main Authors: Jerónimo L. Ulloa, Renata Spina, Agustina Casasco, Patricia B. Petray, Virginia Martino, Miguel A. Sosa, Fernanda M. Frank, Liliana V. Muschietti
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Parasites & Vectors
Subjects:
Sesquiterpene lactones
Smallanthus sonchifolius
Leishmanicidal activity
Trypanocidal activity
In vitro assays
In vivo assays
Online Access:http://link.springer.com/article/10.1186/s13071-017-2509-6

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http://link.springer.com/article/10.1186/s13071-017-2509-6

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