‘Triple clear’: a systematic and comprehensive surgical process for Campanacci grades II and III giant cell tumors of the bone, with or without pathological fracture and slight joint invasion
Abstract Background In recent years, researchers have proposed a number of adjuvant methods for extended curettage of giant cell tumors of the bone. However, various schemes have significant differences in efficacy and safety. Therefore, this article will describe an empirical expanded curettage pro...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2023-03-01
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| Series: | World Journal of Surgical Oncology |
| Online Access: | https://doi.org/10.1186/s12957-023-02982-2 |
| _version_ | 1797853805301202944 |
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| author | Yushan Wang Pengfei Shao Qiaoqiao Tian Haoze Li Jian Li Peng Ren Zhi Lv Jia Lv Junjun Bai Yi Feng |
| author_facet | Yushan Wang Pengfei Shao Qiaoqiao Tian Haoze Li Jian Li Peng Ren Zhi Lv Jia Lv Junjun Bai Yi Feng |
| author_sort | Yushan Wang |
| collection | DOAJ |
| description | Abstract Background In recent years, researchers have proposed a number of adjuvant methods for extended curettage of giant cell tumors of the bone. However, various schemes have significant differences in efficacy and safety. Therefore, this article will describe an empirical expanded curettage protocol, ‘triple clear’, in detail to show the effect of the efficient surgical protocol. Method Patients with Campanacci grades II and III primary GCTB who were treated with either SR (n = 39) or TC (n = 41) were included. Various perioperative clinical indicators, including the therapy modality, operation time, Campanacci grade, and filling material were recorded and compared. The pain level was determined by the visual analog scale. Limb function was determined by the Musculoskeletal Tumour Society (MSTS) score. Follow-up time, recurrence rates, reoperation rates, and complication rates were also recorded and compared. Result The operation time was 135.7 ± 38.4 min in the TC group and 174.2 ± 43.0 min in the SR group (P < 0.05). The recurrence rates were 7.3% in the TC group and 8.3% in the SR group (P = 0.37). The MSTS scores at three months after surgery were 19.8 ± 1.5 in the TC group and 18.8 ± 1.3 in the SR group. The MSTS scores at two years were 26.2 ± 1.2 in the TC group and 24.3 ± 1.4 in the SR group (P < 0.05). Conclusion TC is recommended for patients with Campanacci grade II–III GCTB and for those with a pathological fracture or slight joint invasion. Bone grafts may be more suitable than bone cement in the long term. |
| first_indexed | 2024-04-09T19:55:34Z |
| format | Article |
| id | doaj.art-b36e5d287f8e4f0586fc77d792af8081 |
| institution | Directory Open Access Journal |
| issn | 1477-7819 |
| language | English |
| last_indexed | 2024-04-09T19:55:34Z |
| publishDate | 2023-03-01 |
| publisher | BMC |
| record_format | Article |
| series | World Journal of Surgical Oncology |
| spelling | doaj.art-b36e5d287f8e4f0586fc77d792af80812023-04-03T05:29:29ZengBMCWorld Journal of Surgical Oncology1477-78192023-03-0121111110.1186/s12957-023-02982-2‘Triple clear’: a systematic and comprehensive surgical process for Campanacci grades II and III giant cell tumors of the bone, with or without pathological fracture and slight joint invasionYushan Wang0Pengfei Shao1Qiaoqiao Tian2Haoze Li3Jian Li4Peng Ren5Zhi Lv6Jia Lv7Junjun Bai8Yi Feng9Department of Orthopaedics, The Second Hospital of Shanxi Medical UniversityDepartment of Orthopaedics, The Second Hospital of Shanxi Medical UniversityDepartment of Orthopaedics, The Second Hospital of Shanxi Medical UniversityDepartment of Orthopaedics, The Second Hospital of Shanxi Medical UniversityDepartment of Orthopaedics, The Second Hospital of Shanxi Medical UniversityDepartment of Orthopaedics, The Second Hospital of Shanxi Medical UniversityDepartment of Orthopaedics, The Second Hospital of Shanxi Medical UniversityDepartment of Orthopaedics, The Second Hospital of Shanxi Medical UniversityDepartment of Orthopaedics, The Second Hospital of Shanxi Medical UniversityDepartment of Orthopaedics, The Second Hospital of Shanxi Medical UniversityAbstract Background In recent years, researchers have proposed a number of adjuvant methods for extended curettage of giant cell tumors of the bone. However, various schemes have significant differences in efficacy and safety. Therefore, this article will describe an empirical expanded curettage protocol, ‘triple clear’, in detail to show the effect of the efficient surgical protocol. Method Patients with Campanacci grades II and III primary GCTB who were treated with either SR (n = 39) or TC (n = 41) were included. Various perioperative clinical indicators, including the therapy modality, operation time, Campanacci grade, and filling material were recorded and compared. The pain level was determined by the visual analog scale. Limb function was determined by the Musculoskeletal Tumour Society (MSTS) score. Follow-up time, recurrence rates, reoperation rates, and complication rates were also recorded and compared. Result The operation time was 135.7 ± 38.4 min in the TC group and 174.2 ± 43.0 min in the SR group (P < 0.05). The recurrence rates were 7.3% in the TC group and 8.3% in the SR group (P = 0.37). The MSTS scores at three months after surgery were 19.8 ± 1.5 in the TC group and 18.8 ± 1.3 in the SR group. The MSTS scores at two years were 26.2 ± 1.2 in the TC group and 24.3 ± 1.4 in the SR group (P < 0.05). Conclusion TC is recommended for patients with Campanacci grade II–III GCTB and for those with a pathological fracture or slight joint invasion. Bone grafts may be more suitable than bone cement in the long term.https://doi.org/10.1186/s12957-023-02982-2 |
| spellingShingle | Yushan Wang Pengfei Shao Qiaoqiao Tian Haoze Li Jian Li Peng Ren Zhi Lv Jia Lv Junjun Bai Yi Feng ‘Triple clear’: a systematic and comprehensive surgical process for Campanacci grades II and III giant cell tumors of the bone, with or without pathological fracture and slight joint invasion World Journal of Surgical Oncology |
| title | ‘Triple clear’: a systematic and comprehensive surgical process for Campanacci grades II and III giant cell tumors of the bone, with or without pathological fracture and slight joint invasion |
| title_full | ‘Triple clear’: a systematic and comprehensive surgical process for Campanacci grades II and III giant cell tumors of the bone, with or without pathological fracture and slight joint invasion |
| title_fullStr | ‘Triple clear’: a systematic and comprehensive surgical process for Campanacci grades II and III giant cell tumors of the bone, with or without pathological fracture and slight joint invasion |
| title_full_unstemmed | ‘Triple clear’: a systematic and comprehensive surgical process for Campanacci grades II and III giant cell tumors of the bone, with or without pathological fracture and slight joint invasion |
| title_short | ‘Triple clear’: a systematic and comprehensive surgical process for Campanacci grades II and III giant cell tumors of the bone, with or without pathological fracture and slight joint invasion |
| title_sort | triple clear a systematic and comprehensive surgical process for campanacci grades ii and iii giant cell tumors of the bone with or without pathological fracture and slight joint invasion |
| url | https://doi.org/10.1186/s12957-023-02982-2 |
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