Image quality improvement in adaptive optics scanning laser ophthalmoscopy assisted capillary visualization using B-spline-based elastic image registration.
PURPOSE: To investigate the effect of B-spline-based elastic image registration on adaptive optics scanning laser ophthalmoscopy (AO-SLO)-assisted capillary visualization. METHODS: AO-SLO videos were acquired from parafoveal areas in the eyes of healthy subjects and patients with various diseases. A...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2013-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3827159?pdf=render |
| _version_ | 1818267703089037312 |
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| author | Akihito Uji Sotaro Ooto Masanori Hangai Shigeta Arichika Nagahisa Yoshimura |
| author_facet | Akihito Uji Sotaro Ooto Masanori Hangai Shigeta Arichika Nagahisa Yoshimura |
| author_sort | Akihito Uji |
| collection | DOAJ |
| description | PURPOSE: To investigate the effect of B-spline-based elastic image registration on adaptive optics scanning laser ophthalmoscopy (AO-SLO)-assisted capillary visualization. METHODS: AO-SLO videos were acquired from parafoveal areas in the eyes of healthy subjects and patients with various diseases. After nonlinear image registration, the image quality of capillary images constructed from AO-SLO videos using motion contrast enhancement was compared before and after B-spline-based elastic (nonlinear) image registration performed using ImageJ. For objective comparison of image quality, contrast-to-noise ratios (CNRS) for vessel images were calculated. For subjective comparison, experienced ophthalmologists ranked images on a 5-point scale. RESULTS: All AO-SLO videos were successfully stabilized by elastic image registration. CNR was significantly higher in capillary images stabilized by elastic image registration than in those stabilized without registration. The average ratio of CNR in images with elastic image registration to CNR in images without elastic image registration was 2.10 ± 1.73, with no significant difference in the ratio between patients and healthy subjects. Improvement of image quality was also supported by expert comparison. CONCLUSIONS: Use of B-spline-based elastic image registration in AO-SLO-assisted capillary visualization was effective for enhancing image quality both objectively and subjectively. |
| first_indexed | 2024-12-12T20:26:48Z |
| format | Article |
| id | doaj.art-b36ebb917aaf4d59ac87abea32cae5d2 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-12T20:26:48Z |
| publishDate | 2013-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-b36ebb917aaf4d59ac87abea32cae5d22022-12-22T00:13:08ZengPublic Library of Science (PLoS)PLoS ONE1932-62032013-01-01811e8010610.1371/journal.pone.0080106Image quality improvement in adaptive optics scanning laser ophthalmoscopy assisted capillary visualization using B-spline-based elastic image registration.Akihito UjiSotaro OotoMasanori HangaiShigeta ArichikaNagahisa YoshimuraPURPOSE: To investigate the effect of B-spline-based elastic image registration on adaptive optics scanning laser ophthalmoscopy (AO-SLO)-assisted capillary visualization. METHODS: AO-SLO videos were acquired from parafoveal areas in the eyes of healthy subjects and patients with various diseases. After nonlinear image registration, the image quality of capillary images constructed from AO-SLO videos using motion contrast enhancement was compared before and after B-spline-based elastic (nonlinear) image registration performed using ImageJ. For objective comparison of image quality, contrast-to-noise ratios (CNRS) for vessel images were calculated. For subjective comparison, experienced ophthalmologists ranked images on a 5-point scale. RESULTS: All AO-SLO videos were successfully stabilized by elastic image registration. CNR was significantly higher in capillary images stabilized by elastic image registration than in those stabilized without registration. The average ratio of CNR in images with elastic image registration to CNR in images without elastic image registration was 2.10 ± 1.73, with no significant difference in the ratio between patients and healthy subjects. Improvement of image quality was also supported by expert comparison. CONCLUSIONS: Use of B-spline-based elastic image registration in AO-SLO-assisted capillary visualization was effective for enhancing image quality both objectively and subjectively.http://europepmc.org/articles/PMC3827159?pdf=render |
| spellingShingle | Akihito Uji Sotaro Ooto Masanori Hangai Shigeta Arichika Nagahisa Yoshimura Image quality improvement in adaptive optics scanning laser ophthalmoscopy assisted capillary visualization using B-spline-based elastic image registration. PLoS ONE |
| title | Image quality improvement in adaptive optics scanning laser ophthalmoscopy assisted capillary visualization using B-spline-based elastic image registration. |
| title_full | Image quality improvement in adaptive optics scanning laser ophthalmoscopy assisted capillary visualization using B-spline-based elastic image registration. |
| title_fullStr | Image quality improvement in adaptive optics scanning laser ophthalmoscopy assisted capillary visualization using B-spline-based elastic image registration. |
| title_full_unstemmed | Image quality improvement in adaptive optics scanning laser ophthalmoscopy assisted capillary visualization using B-spline-based elastic image registration. |
| title_short | Image quality improvement in adaptive optics scanning laser ophthalmoscopy assisted capillary visualization using B-spline-based elastic image registration. |
| title_sort | image quality improvement in adaptive optics scanning laser ophthalmoscopy assisted capillary visualization using b spline based elastic image registration |
| url | http://europepmc.org/articles/PMC3827159?pdf=render |
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