ABC Transporter C1 Prevents Dimethyl Fumarate from Targeting Alzheimer’s Disease

ABC Transporter C1 Prevents Dimethyl Fumarate from Targeting Alzheimer’s Disease

Alzheimer’s disease (AD), the leading cause of dementia, is a growing health issue with very limited treatment options. To meet the need for novel therapeutics, existing drugs with additional preferred pharmacological profiles could be recruited. This strategy is known as ‘drug repurposing’. Here, w...

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Bibliographic Details
Main Authors: Luisa Möhle, Katja Stefan, Pablo Bascuñana, Mirjam Brackhan, Thomas Brüning, Ivan Eiriz, Ahmed El Menuawy, Sylvie van Genderen, Irene Santos-García, Anna Maria Górska, María Villa, Jingyun Wu, Sven Marcel Stefan, Jens Pahnke
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Biology
Subjects:
dimethyl fumarate
DMF
Alzheimer’s disease
AD mouse model
drug repurposing
multiple sclerosis
Online Access:https://www.mdpi.com/2079-7737/12/7/932

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