Extracellular Vesicles isolated from Mesenchymal Stromal Cells Modulate CD4<sup>+</sup> T Lymphocytes Toward a Regulatory Profile

Extracellular Vesicles isolated from Mesenchymal Stromal Cells Modulate CD4<sup>+</sup> T Lymphocytes Toward a Regulatory Profile

Mesenchymal stromal cells (MSCs) can generate immunological tolerance due to their regulatory activity in many immune cells. Extracellular vesicles (EVs) release is a pivotal mechanism by which MSCs exert their actions. In this study, we evaluate whether mesenchymal stromal cell extracellular vesicl...

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Bibliographic Details
Main Authors: Flavia Franco da Cunha, Vinicius Andrade-Oliveira, Danilo Candido de Almeida, Tamiris Borges da Silva, Cristiane Naffah de Souza Breda, Mario Costa Cruz, Eliana L. Faquim-Mauro, Marcos Antonio Cenedeze, Meire Ioshie Hiyane, Alvaro Pacheco-Silva, Regiane Aparecida Cavinato, Ana Claudia Torrecilhas, Niels Olsen Saraiva Câmara
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
mesenchymal stromal cells
extracellular vesicles
Th1 polarization
miRNA
metabolism
Online Access:https://www.mdpi.com/2073-4409/9/4/1059

Internet

https://www.mdpi.com/2073-4409/9/4/1059

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