Rapid SARS-CoV-2 Variants Enzymatic Detection (SAVED) by CRISPR-Cas12a

Rapid SARS-CoV-2 Variants Enzymatic Detection (SAVED) by CRISPR-Cas12a

ABSTRACT The continuous and rapid surge of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with high transmissibility and evading neutralization is alarming, necessitating expeditious detection of the variants concerned. Here, we report the development of rapid SARS-CoV-2 varia...

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Bibliographic Details
Main Authors: Jun Yang, Nilakshi Barua, Md Nannur Rahman, Carmen Li, Norman Lo, Kai Yan Yeong, Tsz Fung Tsang, Xiao Yang, Yuk-Yam Cheung, Alan K. L. Tsang, Rickjason C. W. Chan, Eddie Chi-Man Leung, Paul K. S. Chan, Margaret Ip
Format: Article
Language:English
Published: American Society for Microbiology 2022-12-01
Series:Microbiology Spectrum
Subjects:
CRISPR-Cas12a
chimeric crRNA
SARS-CoV-2 variants detection
SAVED
SNP genotyping
short crRNA
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03260-22

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