Development of Flow-Through Cell Dissolution Method for In Situ Visualization of Dissolution Processes in Solid Dosage Forms Using X-ray μCT

Development of Flow-Through Cell Dissolution Method for In Situ Visualization of Dissolution Processes in Solid Dosage Forms Using X-ray μCT

Visualization of the dynamic behavior of pharmaceutical dosage forms during the dissolution process offers a better understanding of the drug release mechanism, enabling the design of customized dosage forms. In this study, an X-ray tomography-based approach is proposed to monitor and analyze the dy...

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Bibliographic Details
Main Authors: Niloofar Moazami Goudarzi, Aseel Samaro, Chris Vervaet, Matthieu N. Boone
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Pharmaceutics
Subjects:
dissolution
μCT
flow-through cell method
contrast agent
3D printing
sustained release
Online Access:https://www.mdpi.com/1999-4923/14/11/2475

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