The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome

Abstract The current model is that the influenza virus polymerase (FluPol) binds either to host RNA polymerase II (RNAP II) or to the acidic nuclear phosphoprotein 32 (ANP32), which drives its conformation and activity towards transcription or replication of the viral genome, respectively. Here, we...

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Detaylı Bibliyografya
Asıl Yazarlar: Tim Krischuns, Benoît Arragain, Catherine Isel, Sylvain Paisant, Matthias Budt, Thorsten Wolff, Stephen Cusack, Nadia Naffakh
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: Nature Portfolio 2024-02-01
Seri Bilgileri:Nature Communications
Online Erişim:https://doi.org/10.1038/s41467-024-45205-2