A case-control study on alcohol and psychiatric disorders as risk factors for drug abuse pattern

We evaluated alcohol and psychiatric disorders as risk factors for the pattern of drug abuse/dependence in a matched case-control study (370 adults). Cases (drug abusers) and controls were selected in the community using the snowball technique and matched by sex, age, and friendship. Information was...

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Main Authors: Claudia S. Lopes, Rosely Sichieri
Format: Article
Language:English
Published: Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz
Series:Cadernos de Saúde Pública
Subjects:
Online Access:http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0102-311X2002000600010&lng=en&tlng=en
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author Claudia S. Lopes
Rosely Sichieri
author_facet Claudia S. Lopes
Rosely Sichieri
author_sort Claudia S. Lopes
collection DOAJ
description We evaluated alcohol and psychiatric disorders as risk factors for the pattern of drug abuse/dependence in a matched case-control study (370 adults). Cases (drug abusers) and controls were selected in the community using the snowball technique and matched by sex, age, and friendship. Information was gathered using the "Composite International Diagnostic Interview" (CIDI). Three patterns of drug abuse/dependence were evaluated: any drug abuse/dependence, only cannabis, and cocaine and other drugs. Logistic conditional regression showed that alcohol dependence was strongly associated with pattern of drug abuse/dependence. Thus, compared to the "no drug abuse group", the odds ratio for association with diagnosis of abuse/dependence on cocaine and other drugs was 10.2 (95% CI: 4.9-21.2), whereas for abuse/dependence on cannabis only, the odds ratio was 1.0. For affective disorders, the odds ratio was 2.0 (95% CI: 1.10-3.64) for the group that received a diagnosis of abuse/dependence on cocaine and other drugs, whereas no association was found for those with abuse/dependence on cannabis only. In conclusion, there is not a homogeneous group of "drug users", and the role of risk factors depends on the drug use pattern.
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spelling doaj.art-b38531e138984ffb93cf604c381c7cd82022-12-21T17:34:40ZengEscola Nacional de Saúde Pública, Fundação Oswaldo CruzCadernos de Saúde Pública0102-311X1678-446418615711575S0102-311X2002000600010A case-control study on alcohol and psychiatric disorders as risk factors for drug abuse patternClaudia S. Lopes0Rosely Sichieri1Universidade do Estado do Rio de JaneiroUniversidade do Estado do Rio de JaneiroWe evaluated alcohol and psychiatric disorders as risk factors for the pattern of drug abuse/dependence in a matched case-control study (370 adults). Cases (drug abusers) and controls were selected in the community using the snowball technique and matched by sex, age, and friendship. Information was gathered using the "Composite International Diagnostic Interview" (CIDI). Three patterns of drug abuse/dependence were evaluated: any drug abuse/dependence, only cannabis, and cocaine and other drugs. Logistic conditional regression showed that alcohol dependence was strongly associated with pattern of drug abuse/dependence. Thus, compared to the "no drug abuse group", the odds ratio for association with diagnosis of abuse/dependence on cocaine and other drugs was 10.2 (95% CI: 4.9-21.2), whereas for abuse/dependence on cannabis only, the odds ratio was 1.0. For affective disorders, the odds ratio was 2.0 (95% CI: 1.10-3.64) for the group that received a diagnosis of abuse/dependence on cocaine and other drugs, whereas no association was found for those with abuse/dependence on cannabis only. In conclusion, there is not a homogeneous group of "drug users", and the role of risk factors depends on the drug use pattern.http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0102-311X2002000600010&lng=en&tlng=encase-control studiesmental disorderssubstance-related disordersmatched-pair analysis
spellingShingle Claudia S. Lopes
Rosely Sichieri
A case-control study on alcohol and psychiatric disorders as risk factors for drug abuse pattern
Cadernos de Saúde Pública
case-control studies
mental disorders
substance-related disorders
matched-pair analysis
title A case-control study on alcohol and psychiatric disorders as risk factors for drug abuse pattern
title_full A case-control study on alcohol and psychiatric disorders as risk factors for drug abuse pattern
title_fullStr A case-control study on alcohol and psychiatric disorders as risk factors for drug abuse pattern
title_full_unstemmed A case-control study on alcohol and psychiatric disorders as risk factors for drug abuse pattern
title_short A case-control study on alcohol and psychiatric disorders as risk factors for drug abuse pattern
title_sort case control study on alcohol and psychiatric disorders as risk factors for drug abuse pattern
topic case-control studies
mental disorders
substance-related disorders
matched-pair analysis
url http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0102-311X2002000600010&lng=en&tlng=en
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