Reviewing recherche presentations of persistent Mullerian duct syndrome: case reports

Abstract Background Persistent Mullerian Duct Syndrome (PMDS) is a type of pseudo-hermaphroditism occurring in males internally due to failure in the Anti Mullerian Hormone (AMH)-dependent sex differentiation pathway. Due to absent Anti Mullerian Hormone (AMH), the adult male has both the Wolffian a...

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Main Authors: Aishwarya Jeyakumar, Rajoo Ramachandran, Rajeswaran Rangasami, Lavanya Jeyakumar, Vignesh Gadupudi
Format: Article
Language:English
Published: SpringerOpen 2022-03-01
Series:The Egyptian Journal of Radiology and Nuclear Medicine
Subjects:
Online Access:https://doi.org/10.1186/s43055-022-00752-w
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author Aishwarya Jeyakumar
Rajoo Ramachandran
Rajeswaran Rangasami
Lavanya Jeyakumar
Vignesh Gadupudi
author_facet Aishwarya Jeyakumar
Rajoo Ramachandran
Rajeswaran Rangasami
Lavanya Jeyakumar
Vignesh Gadupudi
author_sort Aishwarya Jeyakumar
collection DOAJ
description Abstract Background Persistent Mullerian Duct Syndrome (PMDS) is a type of pseudo-hermaphroditism occurring in males internally due to failure in the Anti Mullerian Hormone (AMH)-dependent sex differentiation pathway. Due to absent Anti Mullerian Hormone (AMH), the adult male has both the Wolffian and Mullerian duct derivatives. Considering the limited information available in the existing literature, malignant transformation in PMDS has rarely been reported. Case Presentation In this article we present two cases of PMDS which have complicated in to malignancy with review of literature and histopathological correlation. Both of these patients presented with lower abdominal pain, for which computed tomography of abdomen and pelvis was performed following ultrasound of abdomen and pelvis Both the Wolffian and Mullerian duct derivates were visualized on the above mentioned scans in these genetically confirmed males (46 XY). Conclusion Familiarity with PMDS is necessary to diagnose the condition. Hence, in this article, we report recherche presentations of Persistent Mullerian Duct Syndrome which had complicated into malignancies.
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spelling doaj.art-b387f8081648429484c43826b0a44d1d2022-12-21T22:09:44ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine2090-47622022-03-015311810.1186/s43055-022-00752-wReviewing recherche presentations of persistent Mullerian duct syndrome: case reportsAishwarya Jeyakumar0Rajoo Ramachandran1Rajeswaran Rangasami2Lavanya Jeyakumar3Vignesh Gadupudi4Centre of Excellence In Radiology and Imaging Sciences, Department of Radiology, Sri Ramachandra Institute of Higher Education and ResearchCentre of Excellence In Radiology and Imaging Sciences, Department of Radiology, Sri Ramachandra Institute of Higher Education and ResearchCentre of Excellence In Radiology and Imaging Sciences, Department of Radiology, Sri Ramachandra Institute of Higher Education and ResearchCentre of Excellence In Radiology and Imaging Sciences, Department of Radiology, Sri Ramachandra Institute of Higher Education and ResearchCentre of Excellence In Radiology and Imaging Sciences, Department of Radiology, Sri Ramachandra Institute of Higher Education and ResearchAbstract Background Persistent Mullerian Duct Syndrome (PMDS) is a type of pseudo-hermaphroditism occurring in males internally due to failure in the Anti Mullerian Hormone (AMH)-dependent sex differentiation pathway. Due to absent Anti Mullerian Hormone (AMH), the adult male has both the Wolffian and Mullerian duct derivatives. Considering the limited information available in the existing literature, malignant transformation in PMDS has rarely been reported. Case Presentation In this article we present two cases of PMDS which have complicated in to malignancy with review of literature and histopathological correlation. Both of these patients presented with lower abdominal pain, for which computed tomography of abdomen and pelvis was performed following ultrasound of abdomen and pelvis Both the Wolffian and Mullerian duct derivates were visualized on the above mentioned scans in these genetically confirmed males (46 XY). Conclusion Familiarity with PMDS is necessary to diagnose the condition. Hence, in this article, we report recherche presentations of Persistent Mullerian Duct Syndrome which had complicated into malignancies.https://doi.org/10.1186/s43055-022-00752-wPersistent Mullerian duct syndromeMullerian duct derivativesAnti Mullerian hormoneCryptorchidismEndodermal sinus tumour
spellingShingle Aishwarya Jeyakumar
Rajoo Ramachandran
Rajeswaran Rangasami
Lavanya Jeyakumar
Vignesh Gadupudi
Reviewing recherche presentations of persistent Mullerian duct syndrome: case reports
The Egyptian Journal of Radiology and Nuclear Medicine
Persistent Mullerian duct syndrome
Mullerian duct derivatives
Anti Mullerian hormone
Cryptorchidism
Endodermal sinus tumour
title Reviewing recherche presentations of persistent Mullerian duct syndrome: case reports
title_full Reviewing recherche presentations of persistent Mullerian duct syndrome: case reports
title_fullStr Reviewing recherche presentations of persistent Mullerian duct syndrome: case reports
title_full_unstemmed Reviewing recherche presentations of persistent Mullerian duct syndrome: case reports
title_short Reviewing recherche presentations of persistent Mullerian duct syndrome: case reports
title_sort reviewing recherche presentations of persistent mullerian duct syndrome case reports
topic Persistent Mullerian duct syndrome
Mullerian duct derivatives
Anti Mullerian hormone
Cryptorchidism
Endodermal sinus tumour
url https://doi.org/10.1186/s43055-022-00752-w
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AT lavanyajeyakumar reviewingrecherchepresentationsofpersistentmullerianductsyndromecasereports
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