Nutlin-3 promotes HBV replication by activating mTOR-mediated autophagy

BackgroundCurrently, there are approximately 240 million individuals worldwide suffering from chronic hepatitis B infection, yet a definitive cure remains elusive. In the context of pharmaceutical interventions for this patient population, the potential issue of Hepatitis B virus (HBV) reactivation...

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Autori principali: Shaowei Han, Yuanyuan Li, Junnan Wang, Yong Zhang
Natura: Articolo
Lingua:English
Pubblicazione: Frontiers Media S.A. 2024-11-01
Serie:Acta Virologica
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Accesso online:https://www.frontierspartnerships.org/articles/10.3389/av.2024.12585/full