Carboxylated Poly-L-lysine Potentially Reduces Human Sperm DNA Fragmentation after Freeze-Thawing, and Its Function Is Enhanced by Low-Dose Resveratrol

Carboxylated Poly-L-lysine Potentially Reduces Human Sperm DNA Fragmentation after Freeze-Thawing, and Its Function Is Enhanced by Low-Dose Resveratrol

Sperm DNA fragmentation (SDF) that occurs during the freezing–thawing of sperm may negatively impact the treatment outcomes of assisted reproductive technologies (ART). In a previous study, we developed a human sperm cryopreservation reagent containing carboxylated poly-L-lysine (CPLL) that reduced...

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Bibliographic Details
Main Authors: Ryota Tachibana, Hiroki Takeuchi, Kento Yoshikawa-Terada, Tadashi Maezawa, Mikiko Nishioka, Erina Takayama, Hiroaki Tanaka, Kayo Tanaka, Suong-hyu Hyon, Yuki Gen, Eiji Kondo, Tomoaki Ikeda
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Cells
Subjects:
carboxylated poly-L-lysine
cryopreservation
reactive oxygen species
sperm
sperm DNA fragmentation
antioxidant
Online Access:https://www.mdpi.com/2073-4409/12/22/2585

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