Global ubiquitinome profiling identifies NEDD4 as a regulator of Profilin 1 and actin remodelling in neural crest cells
Here the authors combine multi-omics approaches to uncover a role for ubiquitination and the ubiquitin ligase NEDD4 in targeting the actin binding protein Profilin 1 to regulate actin polymerisation in neural crest cells.
Bibliographic Details
| Main Authors: |
Iman Lohraseb,
Peter McCarthy,
Genevieve Secker,
Ceilidh Marchant,
Jianmin Wu,
Naveid Ali,
Sharad Kumar,
Roger J. Daly,
Natasha L. Harvey,
Hiroshi Kawabe,
Oded Kleifeld,
Sophie Wiszniak,
Quenten Schwarz |
|---|
| Format: | Article
|
|---|
| Language: | English |
|---|
| Published: |
Nature Portfolio
2022-04-01
|
|---|
| Series: | Nature Communications
|
|---|
| Online Access: | https://doi.org/10.1038/s41467-022-29660-3
|
|---|