Time-dependent changes in the microenvironment of injured spinal cord affects the therapeutic potential of neural stem cell transplantation for spinal cord injury

Time-dependent changes in the microenvironment of injured spinal cord affects the therapeutic potential of neural stem cell transplantation for spinal cord injury

<p>Abstract</p> <p>Background</p> <p>The transplantation of neural stem/progenitor cells (NS/PCs) at the sub-acute phase of spinal cord injury, but not at the chronic phase, can promote functional recovery. However, the reasons for this difference and whether it involve...

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Bibliographic Details
Main Authors: Nishimura Soraya, Yasuda Akimasa, Iwai Hiroki, Takano Morito, Kobayashi Yoshiomi, Nori Satoshi, Tsuji Osahiko, Fujiyoshi Kanehiro, Ebise Hayao, Toyama Yoshiaki, Okano Hideyuki, Nakamura Masaya
Format: Article
Language:English
Published: BMC 2013-01-01
Series:Molecular Brain
Subjects:
Spinal cord injury
Neural stem/progenitor cells
Cell transplantation
Chronic phase
Microenvironment
Online Access:http://www.molecularbrain.com/content/6/1/3

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