Mechanism of Action of Magnesium Lithospermate B against Aging and Obesity-Induced ER Stress, Insulin Resistance, and Inflammsome Formation in the Liver

Mechanism of Action of Magnesium Lithospermate B against Aging and Obesity-Induced ER Stress, Insulin Resistance, and Inflammsome Formation in the Liver

Magnesium lithospermate B (MLB) is the biologically active compound of the water-soluble fraction of Salvia miltiorrhiza. Magnesium lithospermate B exhibits various biological functions, including antidiabetic, neuroprotective, and antioxidant effects. However, its beneficial effects on insulin sens...

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Bibliographic Details
Main Authors: Ji won Jeong, Bonggi Lee, Dae Hyun Kim, Hyoung Oh Jeong, Kyoung Mi Moon, Min Jo Kim, Takako Yokozawa, Hae Young Chung
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Molecules
Subjects:
magnesium lithospermate B
PPARβ/δ
ER stress
insulin resistance
inflammasome
aging
Online Access:http://www.mdpi.com/1420-3049/23/9/2098

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