Toxic Effect of Lead Chloride on Antioxidant Enzyme in the Liver and Kidney of Fish
The contamination of aquatic habitats has become a serious problem for sustainability of the fisheries sector in Pakistan. Among different pollutants, heavy metals are very toxic. Their toxicity can be assessed by using antioxidant enzymes as biomarkers. These enzymes protect the living organisms...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wright State University
2016-12-01
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| Series: | Journal of Bioresource Management |
| Subjects: | |
| Online Access: | http://corescholar.libraries.wright.edu/jbm/vol3/iss4/1/ |
| Summary: | The contamination of aquatic habitats has become a serious problem for sustainability
of the fisheries sector in Pakistan. Among different pollutants, heavy metals are very toxic.
Their toxicity can be assessed by using antioxidant enzymes as biomarkers. These enzymes
protect the living organisms from the oxidative stress caused by the heavy metals. Therefore,
the effect of lead chloride (PbCl2) on the peroxidase enzyme activity in the tissues (liver and
kidney) of Cirrhinamrigala was investigated. Four groups of Cirrhinamrigala were exposed,
separately, to 96-hr LC50 concentration of PbCl2 along with its sub-lethal concentrations,
viz.2/3rd, 1/4th and 1/5th for a period of 30 days. Another group of fish was kept in metal free
media as a control. After 30 days, fish were dissected and their liver and kidney isolated and
preserved for enzyme assay. Peroxidase activity in the tissues of PbCl2 exposed
Cirrhinamrigala was compared with the control group. Results revealed that the activity of
peroxidase enzyme in fish organs increased significantly (p<0.05) after exposure to lead
chloride, as compared to control. |
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| ISSN: | 2309-3854 2309-3854 |