Toxic Effect of Lead Chloride on Antioxidant Enzyme in the Liver and Kidney of Fish
The contamination of aquatic habitats has become a serious problem for sustainability of the fisheries sector in Pakistan. Among different pollutants, heavy metals are very toxic. Their toxicity can be assessed by using antioxidant enzymes as biomarkers. These enzymes protect the living organisms...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wright State University
2016-12-01
|
| Series: | Journal of Bioresource Management |
| Subjects: | |
| Online Access: | http://corescholar.libraries.wright.edu/jbm/vol3/iss4/1/ |
| _version_ | 1818200221748822016 |
|---|---|
| author | Bakhtawar Raza Muhammad Javed Faiza Ambreen Fariha Latif |
| author_facet | Bakhtawar Raza Muhammad Javed Faiza Ambreen Fariha Latif |
| author_sort | Bakhtawar Raza |
| collection | DOAJ |
| description | The contamination of aquatic habitats has become a serious problem for sustainability
of the fisheries sector in Pakistan. Among different pollutants, heavy metals are very toxic.
Their toxicity can be assessed by using antioxidant enzymes as biomarkers. These enzymes
protect the living organisms from the oxidative stress caused by the heavy metals. Therefore,
the effect of lead chloride (PbCl2) on the peroxidase enzyme activity in the tissues (liver and
kidney) of Cirrhinamrigala was investigated. Four groups of Cirrhinamrigala were exposed,
separately, to 96-hr LC50 concentration of PbCl2 along with its sub-lethal concentrations,
viz.2/3rd, 1/4th and 1/5th for a period of 30 days. Another group of fish was kept in metal free
media as a control. After 30 days, fish were dissected and their liver and kidney isolated and
preserved for enzyme assay. Peroxidase activity in the tissues of PbCl2 exposed
Cirrhinamrigala was compared with the control group. Results revealed that the activity of
peroxidase enzyme in fish organs increased significantly (p<0.05) after exposure to lead
chloride, as compared to control. |
| first_indexed | 2024-12-12T02:34:13Z |
| format | Article |
| id | doaj.art-b39cc941e5eb4cd6b5010a1280519460 |
| institution | Directory Open Access Journal |
| issn | 2309-3854 2309-3854 |
| language | English |
| last_indexed | 2024-12-12T02:34:13Z |
| publishDate | 2016-12-01 |
| publisher | Wright State University |
| record_format | Article |
| series | Journal of Bioresource Management |
| spelling | doaj.art-b39cc941e5eb4cd6b5010a12805194602022-12-22T00:41:19ZengWright State UniversityJournal of Bioresource Management2309-38542309-38542016-12-013419Toxic Effect of Lead Chloride on Antioxidant Enzyme in the Liver and Kidney of FishBakhtawar Raza0Muhammad Javed1Faiza Ambreen2Fariha Latif3University of Agriculture, Faisalabad, PakistanUniversity of Agriculture, Faisalabad, PakistanUniversity of Agriculture, Faisalabad, Pakistan, faiza_zool@yahoo.comUniversity of Agriculture, Faisalabad, PakistanThe contamination of aquatic habitats has become a serious problem for sustainability of the fisheries sector in Pakistan. Among different pollutants, heavy metals are very toxic. Their toxicity can be assessed by using antioxidant enzymes as biomarkers. These enzymes protect the living organisms from the oxidative stress caused by the heavy metals. Therefore, the effect of lead chloride (PbCl2) on the peroxidase enzyme activity in the tissues (liver and kidney) of Cirrhinamrigala was investigated. Four groups of Cirrhinamrigala were exposed, separately, to 96-hr LC50 concentration of PbCl2 along with its sub-lethal concentrations, viz.2/3rd, 1/4th and 1/5th for a period of 30 days. Another group of fish was kept in metal free media as a control. After 30 days, fish were dissected and their liver and kidney isolated and preserved for enzyme assay. Peroxidase activity in the tissues of PbCl2 exposed Cirrhinamrigala was compared with the control group. Results revealed that the activity of peroxidase enzyme in fish organs increased significantly (p<0.05) after exposure to lead chloride, as compared to control.http://corescholar.libraries.wright.edu/jbm/vol3/iss4/1/Lead toxicityPeroxidase activityLiverKidneyFish |
| spellingShingle | Bakhtawar Raza Muhammad Javed Faiza Ambreen Fariha Latif Toxic Effect of Lead Chloride on Antioxidant Enzyme in the Liver and Kidney of Fish Journal of Bioresource Management Lead toxicity Peroxidase activity Liver Kidney Fish |
| title | Toxic Effect of Lead Chloride on Antioxidant Enzyme in the Liver and Kidney of Fish |
| title_full | Toxic Effect of Lead Chloride on Antioxidant Enzyme in the Liver and Kidney of Fish |
| title_fullStr | Toxic Effect of Lead Chloride on Antioxidant Enzyme in the Liver and Kidney of Fish |
| title_full_unstemmed | Toxic Effect of Lead Chloride on Antioxidant Enzyme in the Liver and Kidney of Fish |
| title_short | Toxic Effect of Lead Chloride on Antioxidant Enzyme in the Liver and Kidney of Fish |
| title_sort | toxic effect of lead chloride on antioxidant enzyme in the liver and kidney of fish |
| topic | Lead toxicity Peroxidase activity Liver Kidney Fish |
| url | http://corescholar.libraries.wright.edu/jbm/vol3/iss4/1/ |
| work_keys_str_mv | AT bakhtawarraza toxiceffectofleadchlorideonantioxidantenzymeintheliverandkidneyoffish AT muhammadjaved toxiceffectofleadchlorideonantioxidantenzymeintheliverandkidneyoffish AT faizaambreen toxiceffectofleadchlorideonantioxidantenzymeintheliverandkidneyoffish AT farihalatif toxiceffectofleadchlorideonantioxidantenzymeintheliverandkidneyoffish |