Detection of fibrotic remodeling of epicardial adipose tissue in patients with atrial fibrillation: Imaging approach based on histological observation

Detection of fibrotic remodeling of epicardial adipose tissue in patients with atrial fibrillation: Imaging approach based on histological observation

Background: Fibrotic remodeling of epicardial adipose tissue (EAT) is crucial for proinflammatory atrial myocardial fibrosis, which leads to atrial fibrillation (AF). Objectives: We tested the hypothesis that the ratio of central to marginal adipocyte diameter in EAT represents its fibrotic remodeli...

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Main Authors: Yumi Ishii, MD, Ichitaro Abe, MD, PhD, Shintaro Kira, MD, PhD, Taisuke Harada, MD, Masayuki Takano, MD, Takahiro Oniki, MD, PhD, Hidekazu Kondo, MD, PhD, Yasushi Teshima, MD, PhD, Kunio Yufu, MD, PhD, Takashi Shuto, MD, PhD, Tomoyuki Wada, MD, PhD, Mikiko Nakagawa, MD, PhD, Tatsuo Shimada, PhD, Yoshiki Asayama, MD, PhD, Shinji Miyamoto, MD, PhD, Naohiko Takahashi, MD, PhD
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Heart Rhythm O2
Subjects:
Atrial fibrillation
Computed tomography
Epicardial adipose tissue
Fat attenuation
Fibrosis
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S2666501821000891

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