The Ability of Some Polysaccharides to Disaggregate Lysozyme Amyloid Fibrils and Renature the Protein
The deposition of proteins in the form of insoluble amyloid fibril aggregates is linked to a range of diseases. The supramolecular architecture of such deposits is governed by the propagation of β-strands in the direction of protofilament growth. In the present study, we analyze the structural chang...
Main Authors: | Olga Makshakova, Liliya Bogdanova, Dzhigangir Faizullin, Diliara Khaibrakhmanova, Sufia Ziganshina, Elena Ermakova, Yuriy Zuev, Igor Sedov |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-02-01
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Series: | Pharmaceutics |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4923/15/2/624 |
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