Elevated Interleukin-31 Levels in Serum, but Not CSF of Dogs with Steroid-Responsive Meningitis-Arteritis Suggest an Involvement in Its Pathogenesis

Elevated Interleukin-31 Levels in Serum, but Not CSF of Dogs with Steroid-Responsive Meningitis-Arteritis Suggest an Involvement in Its Pathogenesis

Steroid-responsive meningitis-arteritis (SRMA) is a predominantly Th-2 immune-mediated disease, but the exact pathomechanism remains unclear. Interleukin-31 (IL-31) is predominantly produced by T cells with a Th-2 phenotype during proinflammatory conditions. We hypothesize that IL-31 might be involv...

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Bibliographic Details
Main Authors: Laura Lemke, Regina Carlson, Katrin Warzecha, Andrea V. Volk, Andrea Tipold, Jasmin Nessler
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Animals
Subjects:
IL-31
SRMA
canine
Th-2 mediated inflammation
MUO
meningoencephalitis of unknown origin
Online Access:https://www.mdpi.com/2076-2615/13/16/2676

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